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Micro-Particles and Gas Dynamics in an Axi-Symmetric Supersonic Nozzle

Abdallah Shaaban; Soliman Salah

Verlag: LAP Lambert Academic Publishing, 2014
ISBN 10: 3659638196 / ISBN 13: 9783659638190
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Titel: Micro-Particles and Gas Dynamics in an ...

Verlag: LAP Lambert Academic Publishing

Erscheinungsdatum: 2014

Einband: Soft cover

Zustand: New


Brand New, Unread Copy in Perfect Condition. A+ Customer Service!. Buchnummer des Verkäufers ABE_book_new_3659638196

Über diesen Titel:

Inhaltsangabe: A new biolistic gene gun for micromolecular drug delivery to human skin has been developed and numerically tested. The device generates supersonic flow to accelerate the mediated microparticles to sufficient speeds to breach the outer human skin layer. The device is referred to as CDN-WPI and consists of; a high pressure gas tank, a convergent-divergent nozzle (C-D), and a constant area mixing duct. The mediated microparticles are entrained from a parallel inlet after the exit of the C-D nozzle. The gas from the high pressure tank accelerates through the C-D nozzle to supersonic speeds which in turn accelerate the powder microparticles through the constant area mixing duct to high speeds. A validated numerical procedure is used to study the two-phase flow dynamics inside the biolistic gun using different geometrical configurations. Different driver gas pressures, gas type (helium and air), adding gas swirl, microparticles types and size are considered in this study. The dimensions of the device C-D nozzle, mixing duct length, and the number of particles inlets are the geometrical configurations studied.

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