This Book is in Good Condition. Clean Copy With Light Amount of Wear. 100% Guaranteed. Summary: PrefaceDrug Absorption, Distribution, Metabolism, and Excretion1. Drug Absorption, Distribution, Metabolism, and Excretion2. Drug Transport3. Parenteral Routes of Drug Administration4. Enteral Routes of Drug Administration5. Factors Influencing Absorption and Bioavailability After EnteralAdministration6. Physicochemical and Formulation Factors Affecting Drug Absorption7. Clinical Factors and Interactions Affecting Drug Absorption8. Drug Distribution9. Drug Metabolism10. Effect of Liver Disease on Drug Metabolism and Pharmacokinetics11. Renal Excretion12. Drug Elimination in Renal ImpairmentThe Mathematics of Pharmacokinetics13. The One-Compartment Open Model with Intravenous Dosage14. The One-Compartment Open Model with First-Order Absorption and Elimination15. Multiple-Dose Kinetics16. Metabolite Pharmacokinetics17. The Two-Compartment Open Model with Intravenous or Oral Administration18. Physiological Pharmacokinetic Models19. Nonlinear PharmacokineticsApplications of Pharmacokinetics in Drug Discovery and Development20. Pharmacokinetics and Toxicokinetics21. Role of Pharmacokinetics in Drug Discovery and Development22. Integration of Pharmacokinetics into Research and DevelopmentAppendixesAppendix I: Computer Methods and Software for Pharmacokinetic Data AnalysisAppendix II: Worked Answers to Problem SetsAppendix III: NomenclatureAppendix IV: GlossaryIndex. Buchnummer des Verkäufers
Inhaltsangabe: Pharmacokinetics is the study of the absorption, distribution, metabolism, and excretion of drugs in humans. This book, written by an internationally known researcher, teaches the basic principles, including drug transport, parenteral and enteral routes of drug administration, and factors affecting drug absorption, distribution, and metabolism. Extensively revised, this edition presents the mathematics of pharmacokinetics with various single- and multi-compartment models including detailed descriptions of metabolite and nonlinear pharmacokinetics. It also describes renal and hepatic drug clearance, and the influence of kidney and liver impairment on these functions. Taking a tutorial approach throughout, the author provides both a clear introduction to pharmacokinetics and a critical look at how this science affects drug discovery and development.
Buchbeschreibung American Chemical Society, 1997. Hardcover. Buchzustand: New. Buchnummer des Verkäufers P110841234817
Buchbeschreibung American Chemical Society, 1997. Hardcover. Buchzustand: New. 2. Buchnummer des Verkäufers DADAX0841234817
Buchbeschreibung American Chemical Society, 1997. Hardcover. Buchzustand: Used: Good. We ship International with Tracking Number! May not contain Access Codes or Supplements. Buy with confidence, excellent customer service! j. Buchnummer des Verkäufers 0841234817D