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Verlag: Raven Press, 1980
ISBN 10: 0890044589ISBN 13: 9780890044582
Anbieter: Zubal-Books, Since 1961, Cleveland, OH, USA
Buch
Zustand: Good. 414 pp., HARDCOVER, ex library, else text clean and binding tight. - If you are reading this, this item is actually (physically) in our stock and ready for shipment once ordered. We are not bookjackers. Buyer is responsible for any additional duties, taxes, or fees required by recipient's country.
Verlag: Springer, 2011
ISBN 10: 3642726690ISBN 13: 9783642726699
Anbieter: WorldofBooks, Goring-By-Sea, WS, Vereinigtes Königreich
Buch
Paperback. Zustand: Very Good. The book has been read, but is in excellent condition. Pages are intact and not marred by notes or highlighting. The spine remains undamaged.
Verlag: Springer, 2013
ISBN 10: 3642252397ISBN 13: 9783642252396
Anbieter: Anybook.com, Lincoln, Vereinigtes Königreich
Buch
Zustand: Good. Volumes 1 and 2. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. Clean from markings. In good all round condition. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,3450grams, ISBN:9783642252396.
Verlag: Lippincott Williams & Wilkins, 1980
ISBN 10: 0890044589ISBN 13: 9780890044582
Anbieter: Books Puddle, New York, NY, USA
Buch
Zustand: New. pp. 414 1st Edition.
Verlag: Lippincott Williams & Wilkins, 1980
ISBN 10: 0890044589ISBN 13: 9780890044582
Anbieter: Majestic Books, Hounslow, Vereinigtes Königreich
Buch
Zustand: New. pp. 414.
Verlag: Springer Berlin Heidelberg, 2012
ISBN 10: 3642627129ISBN 13: 9783642627125
Anbieter: moluna, Greven, Deutschland
Buch Print-on-Demand
Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung für Sie gedruckt. Von A bis Z erfolgreiches Software-HandlingOrientierungshilfe fuer den richtigen MethodenmixPraxis-Anleitung fuer mehr Software-Qualitaet und schnellere Entwick.
Verlag: Springer Berlin, 2011
ISBN 10: 3642726690ISBN 13: 9783642726699
Anbieter: Buchpark, Trebbin, Deutschland
Buch
Zustand: Sehr gut. Gepflegter, sauberer Zustand. 24406431/2 Softcover reprint of the original 1st ed. 1987.
Verlag: Springer, 2006
Anbieter: Antiquariat Thomas Haker GmbH & Co. KG, Berlin, Deutschland
Verbandsmitglied: GIAQ
Buch
Hardcover/Pappeinband. 920 p. Very good. Shrink wrapped. / Sehr guter Zustand. In Folie verschweißt. Sprache: Englisch Gewicht in Gramm: 2204.
Verlag: Springer, 2011
ISBN 10: 3642726690ISBN 13: 9783642726699
Anbieter: booksXpress, Bayonne, NJ, USA
Buch
Soft Cover. Zustand: new.
Verlag: Springer, 2011
ISBN 10: 3642726690ISBN 13: 9783642726699
Anbieter: Lucky's Textbooks, Dallas, TX, USA
Buch
Zustand: New.
Verlag: Springer, 2011
ISBN 10: 3642726690ISBN 13: 9783642726699
Anbieter: Ria Christie Collections, Uxbridge, Vereinigtes Königreich
Buch Print-on-Demand
Zustand: New. PRINT ON DEMAND Book; New; Fast Shipping from the UK. No. book.
Verlag: Springer 2011-12, 2011
ISBN 10: 3642726690ISBN 13: 9783642726699
Anbieter: Chiron Media, Wallingford, Vereinigtes Königreich
Buch
PF. Zustand: New.
Verlag: Springer Berlin Heidelberg Dez 2011, 2011
ISBN 10: 3642726690ISBN 13: 9783642726699
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Der Zusammenhang zwischen Dermatologie und Rheuma spielt in der Klinik eine große Rolle und erstreckt sich auf zahlreiche Fachgebiete. In diesem Buch wird dieses Thema von hervorragenden Fachwissenschaftlern ausführlich abgehandelt. Der thematische Bezug reicht von infekt- und medikamentenallergischen Haut- und Gelenkveränderungen über die psoriatische Skelettbeteiligung bis hin zu den sogenannten Kollagenosen, als deren wichtigster Vertreter die zirkumskripte und progressive systemische Sklerodermie gilt. In allen Beiträgen werden - soweit sie nicht die Grundlagenforschung betreffen - Diagnostik, Klinik und Therapie ausführlich besprochen. 588 pp. Deutsch.
Verlag: Springer Berlin Heidelberg, 2011
ISBN 10: 3642726690ISBN 13: 9783642726699
Anbieter: AHA-BUCH GmbH, Einbeck, Deutschland
Buch
Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Der Zusammenhang zwischen Dermatologie und Rheuma spielt in der Klinik eine große Rolle und erstreckt sich auf zahlreiche Fachgebiete. In diesem Buch wird dieses Thema von hervorragenden Fachwissenschaftlern ausführlich abgehandelt. Der thematische Bezug reicht von infekt- und medikamentenallergischen Haut- und Gelenkveränderungen über die psoriatische Skelettbeteiligung bis hin zu den sogenannten Kollagenosen, als deren wichtigster Vertreter die zirkumskripte und progressive systemische Sklerodermie gilt. In allen Beiträgen werden - soweit sie nicht die Grundlagenforschung betreffen - Diagnostik, Klinik und Therapie ausführlich besprochen.
Verlag: Springer, 2011
ISBN 10: 3642726690ISBN 13: 9783642726699
Anbieter: Books Puddle, New York, NY, USA
Buch
Zustand: New. pp. 588.
Verlag: Springer Berlin Heidelberg, 2011
ISBN 10: 3642726690ISBN 13: 9783642726699
Anbieter: moluna, Greven, Deutschland
Buch Print-on-Demand
Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Der Zusammenhang zwischen Dermatologie und Rheuma spielt in der Klinik eine grosse Rolle und erstreckt sich auf zahlreiche Fachgebiete. In diesem Buch wird dieses Thema von hervorragenden Fachwissenschaftlern ausfuehrlich abgehandelt. Der thematische Bezug re.
Verlag: Springer, 2010
ISBN 10: 3540898905ISBN 13: 9783540898900
Anbieter: ThriftBooks-Dallas, Dallas, TX, USA
Buch
Hardcover. Zustand: Fair. No Jacket. Readable copy. Pages may have considerable notes/highlighting. ~ ThriftBooks: Read More, Spend Less 2.9.
Verlag: Springer Berlin Heidelberg, 2010
ISBN 10: 3540898905ISBN 13: 9783540898900
Anbieter: moluna, Greven, Deutschland
Buch Print-on-Demand
Gebunden. Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. A landmark in the continuously changing world of drugsEasy-to-use, method-orientated overview on all aspects of Clinical PharmacologyEssential reading for pharmacologists, physicians, medicinal chemists and pharmacists at research institute.
Verlag: Springer Berlin Heidelberg Dez 2010, 2010
ISBN 10: 3540898905ISBN 13: 9783540898900
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series 'Drug Discovery and Evaluation' in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series 'Pharmacological Assays' comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume 'Safety and Pharmacokinetic Assays'. Only then are first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: 'Methods in Clinical Pharmacology'. 576 pp. Englisch.
Verlag: Springer Berlin Heidelberg, 2010
ISBN 10: 3540898905ISBN 13: 9783540898900
Anbieter: AHA-BUCH GmbH, Einbeck, Deutschland
Buch
Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series 'Drug Discovery and Evaluation' in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series 'Pharmacological Assays' comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume 'Safety and Pharmacokinetic Assays'. Only then are first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: 'Methods in Clinical Pharmacology'.
Verlag: Springer, 2013
ISBN 10: 3642252397ISBN 13: 9783642252396
Anbieter: Basi6 International, Irving, TX, USA
Buch
Zustand: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.
Verlag: Springer, 2013
ISBN 10: 3642252397ISBN 13: 9783642252396
Anbieter: Books Puddle, New York, NY, USA
Buch
Zustand: New. pp. xxiv + 1404 2nd Edition.
Verlag: Springer, 2013
ISBN 10: 3642252397ISBN 13: 9783642252396
Anbieter: GF Books, Inc., Hawthorne, CA, USA
Buch
Zustand: New. Book is in NEW condition.
Verlag: Springer, 2013
ISBN 10: 3642252397ISBN 13: 9783642252396
Anbieter: GF Books, Inc., Hawthorne, CA, USA
Buch
Zustand: Fine. Book is in Used-LikeNew condition. Pages and cover are clean and intact. Used items may not include supplementary materials such as CDs or access codes. May show signs of minor shelf wear.
Verlag: Springer, 2013
ISBN 10: 3642252397ISBN 13: 9783642252396
Anbieter: Book Deals, Tucson, AZ, USA
Buch
Zustand: New. New! This book is in the same immaculate condition as when it was published.
Verlag: Springer Berlin Heidelberg, 2013
ISBN 10: 3642252397ISBN 13: 9783642252396
Anbieter: moluna, Greven, Deutschland
Buch Print-on-Demand
Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. A landmark in the continuously changing world of drugsEssential reading for scientists and managers in the pharmaceutical industry involved in drug finding, drug development and decision making in the development processOf use for governmen.
Verlag: Springer 2010-12-15, 2010
ISBN 10: 3540898905ISBN 13: 9783540898900
Anbieter: Chiron Media, Wallingford, Vereinigtes Königreich
Buch
Hardcover. Zustand: New.
Verlag: Springer, 2013
ISBN 10: 3642252397ISBN 13: 9783642252396
Anbieter: Majestic Books, Hounslow, Vereinigtes Königreich
Buch
Zustand: New. pp. xxiv + 1404 243 Illus.
Verlag: Springer, 2013
ISBN 10: 3642252397ISBN 13: 9783642252396
Anbieter: GF Books, Inc., Hawthorne, CA, USA
Buch
Zustand: Good. Book is in Used-Good condition. Pages and cover are clean and intact. Used items may not include supplementary materials such as CDs or access codes. May show signs of minor shelf wear and contain limited notes and highlighting.
Verlag: Springer Berlin Heidelberg Feb 2013, 2013
ISBN 10: 3642252397ISBN 13: 9783642252396
Anbieter: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Deutschland
Buch Print-on-Demand
Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Safety aspects have become an outstanding issue in the process of drug discovery and development. Until 15 years ago safety aspects were addressed by pharmacological testing of the selected compound in high doses in tests directed at indications other than the intended indication of the new compound. These tests were followed by pharmacokinetic studies, which were mainly aimed at confirming of a suitable half-life time and at oral activity. Safety aspects relied mostly on toxicity studies, which however gave information on changes of organ structure rather than on organ function. Toxicological and pharmacokinetic studies were adapted to the progress of studies in clinical pharmacology and clinical trails. But the success rate in the pharmaceutical industry and the introduction of new chemical entities to the market per year dropped dramatically, whereas the development time for a new compound increased, sometimes exceeding the patent protection. A change of strategy was therefore adopted, involving the following changes: - Parallel instead of sequential involvement of the various disciplines (multidimensional compound optimization).- The term 'Safety Pharmacology' was coined. The International Conference on Harmonization (ICH) founded a Safety Pharmacology Working Group. Easily accessible and the most informative tests now have to be selected.- Exposure of a drug to the body by pharmacokinetic studies on absorption, distribution, metabolism and excretion has to be investigated at an early stage of development and can contribute to the selection of a compound for development. Toxicology experienced major achievements by the introduction of new methods, e.g., in silico methods, toxicogenomics and toxicoproteomics.The book is a landmark in the continuously changing world of drugs. As such it is important reading for many groups: not only for all students of pharmacology and toxicology but also for physicians, especially those involved in clinical trials of drugs, and for pharmacists who have to know the safety requirements of drugs.The book is absolutely essential for scientists and managers in the pharmaceutical industry who are involved in drug finding, drug development and decision making in the development process.In particular, the book will be of use for government institutions and committees working on official guidelines for drug evaluation worldwide. 1452 pp. Englisch.