Cyclic GMP: Synthesis, Metabolism, and Function (Volume 26) (Advances in Pharmacology, Volume 26, Band 26) - Hardcover

Hardcover

ISBN 10: 0120329263 ISBN 13: 9780120329267

Verlag: Academic Press, 1994

Inhaltsangabe

This volume is dedicated to the topic of cyclic GMP. Chapters include discussions on the guanylyl cyclase and phosphodiesterase isoenzyme families for cyclic GMP synthesis and hydrolysis, cyclic GMP-dependent protein kinases, and various hormones and ligands that regulate cyclic GMP formation and/or metabolism. Several chapters also deal with some of the effects of cyclic GMP on other second messengers such as calcium ion transport and smooth muscle relaxation. Some clinical studies with cyclic GMP and atrial natriuretic peptide are also discussed. The last chapter raises many important questions in the field that remain to be addressed.

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Über die Autorin bzw. den Autor

Ferid Murad was born in Whiting, Indiana. Working concurrently on an M.D. and Ph.D. in Pharmacology, Dr. Murad graduated with both degrees from Case Western Reserve University, Cleveland, Ohio, in 1965. His many honors include the Alfred S. Maschke Award for Clinical Excellence from Case Western Reserve University in 1965. He has held several distinguished positions, including Acting Chairman in the Department of Medicine and Acting Division Chief, Division of Respiratory Medicine at Stanford University. He currently is CEO and President of Molecular Geriatrics Corporation in Lake Bluff, Illinois. Dr. Murad is married and has five children.

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Praise for the Serial
"The book provides superb reading material which chemists and pharmacologists interested in the area of chemotherapy will surely enjoy reading." --JOURNAL OF PHARMACEUTICAL SCIENCES

This volume is dedicated to the topic of cyclic GMP. Chapters include discussions on the guanylyl cyclase and phosphodiesterase isoenzyme families for cyclic GMP synthesis and hydrolysis, cyclic GMP-dependent protein kinases, and various hormones and ligands that regulate cyclic GMP formation and/or metabolism. Several chapters also deal with some of the effects of cyclic GMP on other second messangers such as calcium ion transport and smooth muscle relaxation. Some clinical studies with cyclic GMP and atrial natriuretic peptide are also discussed. The last chapter raises many important questions in the field that remain to be addressed.

Key Features

• Chapters discuss:
• Isoforms of guanylyl cyclase and phosphodiesterase isoenzyme families for cyclic GMP synthesis and hydrolysis
• Cyclic GMP-dependent protein kinase
• Hormones and ligands that regulate GMP formation and/or metabolism
• Effects of cyclic GMP on other second messengers and some functions such as smooth muscle relaxation and ion transport
• Clinical studies with cyclic GMP and atrial natriuretic peptide
• Important questions and experiments for the future

Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular basis of drug action, whether applied or experimental.

Details zur Ausgabe

• Verlag: Academic Press
• Erscheinungsdatum: 1994
• Sprache: Englisch
• ISBN 10: 0120329263
• ISBN 13: 9780120329267
• Einband: Gebundene Ausgabe
• Anzahl der Seiten: 335
• Herausgeber: Murad Ferid
• Kontakt zum Hersteller: Academic Press; https://shop.elsevier.com/; ; 230 PARK AVENUE, SUITE 800; NY; NY; 10169; USA
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