Methods in Cell Biology: Functional Organization of the Nucleus : A Laboratory Guide (35) - Hardcover

Hamkalo, Barbara A.

 
9780125641357: Methods in Cell Biology: Functional Organization of the Nucleus : A Laboratory Guide (35)

Inhaltsangabe

A text intended for researchers and students in cell biology, genetics and molecular biology, developmental biology, biochemistry and biophysics. The complex problem of the relationship between nuclear structure and function demands a multidisciplinary, multifaceted approach. This laboratory guide is designed for researchers, from graduate students to professors, who need detailed protocols and general discussions on a broad range of techniques. The volume presents a selection of different methodological approaches for the analysis of nuclear structure and function - from cytological to molecular to genetic. These include visualization of nucleic acid sequences using hybridization probes, visualization of proteins using immunological probes, isolation of chromatin fractions, mapping "in vitro" protein-DNA interactions, reconstitution of functional templates and nuclear substructures, and genetic approaches to identifying and characterizing chromosomal components.

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9780123219206: Methods in Cell Biology: Functional Organization of the Nucleus - A Laboratory Guide

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ISBN 10:  0123219205 ISBN 13:  9780123219206
Verlag: Academic Press Inc, 1991
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