Stellate Cells in Health and Disease is a comprehensive reference providing the most up-to-date knowledge and perspectives on the function of stellate cells affecting the liver and other organs. The text presents comprehensive coverage of their already established role in hepatic fibrosis along with the newer emerging evidence for stellate cell participation in the liver cell (hepatocyte) survival and regeneration, hepatic immunobiology, transplant tolerance, and liver cancer. Chapters describe both animal and human research and the relevance of findings from animal research to human pathophysiology, and also contain sections on future directions which will be of special interest to basic and clinical researchers working on liver fibrosis, hepatic biology, and pathobiology.
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Dr. Chandrashekhar Gandhi is a professor within the department of Surgery at the University of Cincinnati. His laboratory focuses on the mechanisms of intercellular communications that regulate the structure and function of the liver in physiology and pathology. Present research elucidates specific molecular and biochemical mechanisms underlying effects of stellate cells. Dr. Gandhi is a member of the American Association for Advancement of Science, The New York Academy of Sciences, American Society for Biochemistry and Molecular Biology, International Liver Transplantation Society, American Association for the Study of Liver Diseases, and the American Society for Investigative Pathology. He has contributed over 70 published research articles and owns the patent for “Diagnostic and Therapeutic Uses of Augmenter of Liver Regeneration (ALR) in Inflammatory Conditions” (PCT/US2008/075440).
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