GPCR Signaling in Cancer: Volume 145 (Advances in Cancer Research, Volume 145) - Hardcover

Hardcover

ISBN 10: 0128202300 ISBN 13: 9780128202302

Verlag: Academic Press, 2020

Inhaltsangabe

GPCR Signaling in Cancer, Volume 145, the latest release in the Advances in Cancer Research series, highlights recent developments in the area of GPCRs and cancer biology. Chapters included in this volume cover several GPCRs and their downstream effectors as case examples to highlight their fundamental understanding and therapeutic potential. Specific chapters address the Role of GRKs and beta-arrestins in cancer, Atypical GPCRs in cancer, the Role of a chemokine receptor (CCR) 5 in cancer, Targeting G protein-coupled receptors for therapeutics in cancer, Emerging GPCR signaling pathways in cancer, and more.

G protein-coupled receptors (GPCRs) constitute a large family of cell surface receptors which are involved in nearly every cellular and physiological event. These receptors can recognize a broad array of ligands and they are targeted by nearly one third of the currently prescribed drugs including anti-cancer therapeutics.

• Covers the latest concepts in GPCR signaling and their relevancy to cancer biology
• Presents new indications for anti-cancer therapeutic programs
• Includes sections on cross-talk and signaling networks of GPCRs and effectors in molecular oncology and therapeutics

Über diesen Titel

Über die Autorin bzw. den Autor

Dr. Arun K. Shukla is a world leader in the field of GPCR biology and he is currently a Professor in the Department of Biological Sciences and Bioengineering at the Institute of Technology, Kanpur in India. Dr. Shukla’s research program is focused on understanding the structure, function and regulation of G protein-coupled receptors with a long-term of designing novel therapeutics with minimized side-effects.

Details zur Ausgabe

• Verlag: Academic Press
• Erscheinungsdatum: 2020
• ISBN 10: 0128202300
• ISBN 13: 9780128202302
• Einband: Tapa dura
• Sprache: Englisch
• Anzahl der Seiten: 166
• Herausgeber: Shukla Arun K.
• Kontakt zum Hersteller: Nicht verfügbar