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Inborn Errors of Immunity: A Practical Guide - Softcover

 
9780128210284: Inborn Errors of Immunity: A Practical Guide

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Awareness among clinicians about PIDs, which consist of more than 400 different entities, plays an important role in ensuring that patients receive a timely diagnosis. Furthermore, clinicians who are educated about PIDs can give their patients access to optimal management of their condition, thus helping the patient achieve a better quality-of-life and long-term prognosis. Inborn Errors of Immunity: A Practical Guide provides the most up-to-date information for busy students, nurses, clinical residents, practicing physicians, and even basic researchers. Readers will benefit from a well-structured breakdown of complicated PID diseases, including approaches to their clinical signs/symptoms and immunologic/laboratory findings.

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Über die Autorinnen und Autoren

Asghar Aghamohammadi was a Professor in Pediatrics and Clinical Immunology, at the Tehran University of Medical Sciences (TUMS) in Iran. He directed the Research Center for Immunodeficiencies (RCID), the pre-eminent centre in Iran for primary immunodeficiency. He completed a fellowship in Great Ormond Street Hospital, UK and earned a PhD from the University of Toyama, Japan. His work focused on primary immunodeficiency, including primary antibody deficiency disorders, molecular diagnosis, and patient treatment and management. His work has been widely published and referred to in his field.

Hassan Abolhassani is a leading member of the Junior Faculty at the Karolinska Institute (KI) and a team leader at Division of Clinical Immunology in the Department of Laboratory Medicine, KI in Sweden. He received his MD and his first PhD in Immunogenetics from TUMS and his second PhD in Clinical Immunology from the KI. His work focuses on the gene discovery and pathogenesis of primary antibody deficiency and the immune pathways involved, to help physicians and immunologists understand immune-related genes with unknown functions. He has received numerous academic awards and is widely published in the field.

Professor Nima Rezaei gained his medical degree (MD) from Tehran University of Medical Sciences and subsequently obtained an MSc in Molecular and Genetic Medicine and a PhD in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also spent a short-term fellowship of Pediatric Clinical Immunology and Bone Marrow Transplantation in the Newcastle General Hospital. Professor Rezaei is now the Full Professor of Immunology and Vice Dean of Research, School of Medicine, Tehran University of Medical Sciences, and the co-founder and Head of the Research Center for Immunodeficiencies. He is also the founding President of the Universal Scientific Education and Research Network (USERN). Professor Rezaei has already been the Director of more than 55 research projects and has designed and participated in several international collaborative projects. Professor Rezaei is an editorial assistant or board member for more than 30 international journals. He has edited more than 35 international books, has presented more than 500 lectures/posters in congresses/meetings, and has published more than 1,000 scientific papers in the international journals.

Reza Yazdani, PhD, is an Assistant Professor and Vice President of the Research Center for Immunodeficiencies (RCID) at Tehran University of Medical Sciences, the leading institution for the study of inborn errors of immunity (IEI) in Iran. He earned his PhD in Medical Immunology from Isfahan University of Medical Sciences, Iran, and completed a postdoctoral fellowship at Thomas Jefferson University, USA. His research focuses on the pathogenesis and diagnosis of IEIs, with particular expertise in the application of flow cytometry. He has received numerous awards and honors and has published over 160 scientific papers in international journals. He is honored as the top 1% of highly cited scientific researchers in the field of Immunology, Essential Science Indicators (ESI, Web of Science). He was selected as the Best Young Researcher in Medical Sciences at the Avicenna Festival 2025. He also serves on the editorial boards of several international journals.

Von der hinteren Coverseite

Primary immunodeficiency disorders (PIDs) are a group of inborn disorders comprising defects in one or more components of the immune system. Awareness among clinicians about PIDs plays a key role in the early diagnosis of these disorders, in their optimal treatment and in patient outcomes. Inborn Errors of Immunity: A Practical Guide covers all clinical aspects of these disorders in rapidly digestible format. This title promotes awareness among physicians concerning the diagnosis and management of PIDs, based on clinical short notes, and illustrations. This book provides physicians, particularly those involved with pediatrics, allergies and immunology, a set of lecture notes that they can use to quickly familiarize themselves with the field, and find appropriate information and solutions, in a short amount of time. Key sections include approaches to: Combined immunodeficiency; well-defined PID syndromes; predominantly antibody deficiencies; diseases of immune dysregulation; phagocyte disorders; innate immunity deficiencies; autoinflammatory disorders; complement deficiencies; phenocopies of inborn errors of immunity; Ig replacement therapy; and HCST therapy. This eminently practical book of short notes offers a comprehensive reference for busy clinicians who nevertheless need to be familiar with the relevant clinical aspects of PIDs.

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