Human Pluripotent Stem Cell Derived Organoid Models (Volume 159) (Methods in Cell Biology, Volume 159, Band 159) - Hardcover

Hardcover

ISBN 10: 0128215313 ISBN 13: 9780128215319

Verlag: Academic Press, 2020

Inhaltsangabe

Human Pluripotent Stem Cell Derived Organoid Models, Volume 159 highlights recent and emerging advances that describe organoid differentiation protocols for the different organ systems that implement organoids as tools to understand complexity and maturation, high content drug screening, disease modeling, development and evolution. Specific chapters in this new release include Pluripotent stem cell derived gastric organoids, Pluripotent stem cell derived esophageal organoids, Pluripotent stem cell derived small intestinal organoids, Pluripotent stem cell derived colonic organoids, Pluripotent stem cell intestinal organoids with an Enteric Nervous System, Pluripotent stem cell derived airway organoids, Pluripotent stem cell derived alveolar organoids, and much more.

Über diesen Titel

Über die Autorin bzw. den Autor

Jason R. Spence, PhD, is an Associate Professor of Internal Medicine, Cell and Developmental Biology and Biomedical Engineering at the University of Michigan Medical School. He attended Canisius College in Buffalo, NY, as an undergraduate. He attended graduate school at Miami University (Ohio) where his research focused on understanding mechanisms that drive regeneration and tissue repair in unique model organisms that maintain regenerative ability throughout life, including Notophthalmus viridescens (Eastern Newt), Ambystoma mexicanum (Axolotl) and the chick. He performed postdoctoral research Cincinnati Children’s Hospital, where he turned his focus to understanding mechanisms that regulate embryonic development of endoderm-derived tissue (pancreas, liver, intestine) and utilized human pluripotent stem cells (hPSCs) to understand human differentiation and development. During this time, he pioneered methods to differentiate 3-dimensional intestinal organoids from human pluripotent stem cells.
In 2011, Dr. Spence joined the faculty of the University of Michigan Medical School. The focus of the Spence lab include using 3-dimensional organoid human models to study human development and disease, with research focused on understanding intestinal, lung and esophageal development, homeostasis and disease.

Details zur Ausgabe

• Verlag: Academic Press
• Erscheinungsdatum: 2020
• Sprache: Englisch
• ISBN 10: 0128215313
• ISBN 13: 9780128215319
• Einband: Gebundene Ausgabe
• Anzahl der Seiten: 336
• Herausgeber: Spence J.
• Kontakt zum Hersteller: Nicht verfügbar
• Verantwortliche Person: gpsr@libri.de; gpsr@libri.de; ; Europaallee 1; Bad Hersfeld; 36244; Deutschland