Why do we age? Is aging inevitable? Will advances in medical knowledge allow us to extend the human lifespan beyond its present limits? Because growing old has long been the one irreducible reality of human existence, these intriguing questions arise more often in the context of science fiction than science fact. But recent discoveries in the fields of cell biology and molecular genetics are seriously challenging the assumption that human lifespans are beyond our control.
With such discoveries in mind, noted cell biologist William R. Clark clearly and skillfully describes how senescence begins at the level of individual cells and how cellular replication may be bound up with aging of the entire organism. He explores the evolutionary origin and function of aging, the cellular connections between aging and cancer, the parallels between cellular senescence and Alzheimer's disease, and the insights gained through studying human genetic disorders--such as Werner's syndrome--that mimic the symptoms of aging. Clark also explains how reduction in caloric intake may actually help increase lifespan, and how the destructive effects of oxidative elements in the body may be limited by the consumption of antioxidants found in fruits and vegetables. In a final chapter, Clark considers the social and economic aspects of living longer, the implications of gene therapy on senescence, and what we might learn about aging from experiments in cloning.
This is a highly readable, provocative account of some of the most far-reaching and controversial questions we are likely to ask in the next century.
Die Inhaltsangabe kann sich auf eine andere Ausgabe dieses Titels beziehen.
Professor Emeritus of Immunology at UCLA and an internationally recognized authority on cellular immune reactions,William R. Clark is the author of The New Healers: Molecular Medicine in the Twenty-First Century, Sex and the Origins of Death, andAt War Within: The Double Edged Sword of Immunity, all published by OUP.
„Über diesen Titel“ kann sich auf eine andere Ausgabe dieses Titels beziehen.
Anbieter: World of Books (was SecondSale), Montgomery, IL, USA
Hardback. Zustand: Very Good. This work covers ageing from a fundamental cell biological perspective. The evolution and developmental genetics of senescence are explained clearly. All the various theories of ageing - the Hayflick limit and telomeric shortening as a possible biological clock, the impacts of somatic mutations, oxidative stress, accumulation of waste materials in cells with age - are explained and critically assessed. The author presents vivid case accounts about disorders that open windows on to the ageing process. The impacts of ageing on the brain and nervous system are given special attention, as are the effects of caloric restriction on maximum lifespan. Bestandsnummer des Verkäufers 00087973557
Anzahl: 2 verfügbar
Anbieter: BooksRun, Philadelphia, PA, USA
Hardcover. Zustand: Very Good. It's a well-cared-for item that has seen limited use. The item may show minor signs of wear. All the text is legible, with all pages included. It may have slight markings and/or highlighting. Bestandsnummer des Verkäufers 0195125932-11-1
Anzahl: 1 verfügbar
Anbieter: ThriftBooks-Atlanta, AUSTELL, GA, USA
Hardcover. Zustand: Very Good. No Jacket. May have limited writing in cover pages. Pages are unmarked. ~ ThriftBooks: Read More, Spend Less. Bestandsnummer des Verkäufers G0195125932I4N00
Anzahl: 1 verfügbar
Anbieter: Goodwill Books, Hillsboro, OR, USA
Zustand: good. Signs of wear and consistent use. Bestandsnummer des Verkäufers GICWV.0195125932.G
Anzahl: 1 verfügbar
Anbieter: Wonder Book, Frederick, MD, USA
Zustand: As New. Like New condition. Very Good dust jacket. A near perfect copy that may have very minor cosmetic defects. Bestandsnummer des Verkäufers G05I-01143
Anzahl: 1 verfügbar
Anbieter: Wonder Book, Frederick, MD, USA
Zustand: Very Good. Very Good condition. Very Good dust jacket. A copy that may have a few cosmetic defects. May also contain light spine creasing or a few markings such as an owner's name, short gifter's inscription or light stamp. Bestandsnummer des Verkäufers K09A-04212
Anzahl: 2 verfügbar
Anbieter: Better World Books, Mishawaka, IN, USA
Zustand: Very Good. Former library copy. Pages intact with possible writing/highlighting. Binding strong with minor wear. Dust jackets/supplements may not be included. Includes library markings. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good. Bestandsnummer des Verkäufers GRP101974344
Anzahl: 1 verfügbar
Anbieter: Better World Books, Mishawaka, IN, USA
Zustand: Good. Pages intact with minimal writing/highlighting. The binding may be loose and creased. Dust jackets/supplements are not included. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good. Bestandsnummer des Verkäufers 3142128-6
Anzahl: 1 verfügbar
Anbieter: World of Books Inc, Montgomery, IL, USA
Hardback. Zustand: Very Good. This work covers ageing from a fundamental cell biological perspective. The evolution and developmental genetics of senescence are explained clearly. All the various theories of ageing - the Hayflick limit and telomeric shortening as a possible biological clock, the impacts of somatic mutations, oxidative stress, accumulation of waste materials in cells with age - are explained and critically assessed. The author presents vivid case accounts about disorders that open windows on to the ageing process. The impacts of ageing on the brain and nervous system are given special attention, as are the effects of caloric restriction on maximum lifespan. Bestandsnummer des Verkäufers CIN0195125932VG
Anzahl: 2 verfügbar
Anbieter: Steven Edwards, Coalmont, TN, USA
Hard cover. Sewn binding. Cloth over boards. 234 p. Contains: Illustrations. Audience: General/trade. Clean, tight copy. Very good in very good dust jacket. Bestandsnummer des Verkäufers Alibris0009788
Anzahl: 1 verfügbar