The Biology and Clinical Applications of Interleukin-2 - Hardcover

Hardcover

ISBN 10: 0199631379 ISBN 13: 9780199631377

Verlag: Oxford University Press, 1991

Inhaltsangabe

The molecular structure of interleukin-2 (IL-2) and that of its receptor subunits provide a basis for understanding lymphocyte activation by IL-2 and the generation of effector cells capable of mediating cytotoxicity towards tumors. This book provides an up-to-date account of IL-2, its effect on lymphocyte function, and clinical applications. Internationally know experts review the molecular aspects of cell signalling, giving insight on the in vivo pathways of activation likely to be important in determining clinical responses. They also examine the use of cytokines, particularly IL-2, in the treatment of cancer, and describe the results of recent clinical trials using IL-2, as well as of adoptive cell therapy. Providing a clear account of recent progress, the book also reviews the problems involved in attempting to improve the therapeutic benefit of IL-2, along with the importance of mechanisms which subverse IL-2 responses. This is the most up-to-date account of molecular research and clinical trials in this area, and will be of great benefit to students and researchers in immunology, pharmacology, biochemistry, and oncology who are interested in this vitally important topic.

Details zur Ausgabe

• Verlag: Oxford University Press
• Erscheinungsdatum: 1991
• Sprache: Englisch
• ISBN 10: 0199631379
• ISBN 13: 9780199631377
• Einband: Gebundene Ausgabe
• Anzahl der Seiten: 200
• Herausgeber: Rees R. C.
• Kontakt zum Hersteller: ORIGINAL KAISER; https://corp.oup.com/; ; Via Liguria 4; San Giuliano Milanese ; MI; 20098; Italien