MHC Volume 1: A Practical Approach (Practical Approach Series) (Vol 1) (The Practical Approach Series, Band 180) - Softcover

Fernandez, N.

Softcover

ISBN 10: 0199635536 ISBN 13: 9780199635535

Verlag: IRL Press, 1997

Inhaltsangabe

The major histocompatibility complex is the subject of much research in the immunology field. There is a great deal of interest in MHC proteins and their function as antigen presenting molecules, and many immunology laboratories are investigating biochemical and genetic techniques to study these molecules. The identification of peptide transporter genes and the elution of peptides from MHC molecules illustrate how rapidly our understanding of the MHC locus has advanced. This volume brings together the technologies which make these advances possible. It explains in detail the process such as peptide translocation into the ER, the application of mass spectrometry to the analysis of peptides bound to MHC, and signal detection via MHC class II molecules, which lead to either activation or cell death. The book is a comprehensive and thorough guide to the field of MHC research that graduates, post doctoral researchers, and academic staff and clinicians will find invaluable.

Über diesen Titel

Über die Autorin bzw. den Autor

Dr Nelson Fernandez, Dept of Biological and Chemical Sciences, University of Essex, Wivenhoe Park, Colchester CO4 3SQ, UK. Tel: 01206 873330. Fax: 01206 872592. Email: nelson@essex.ac.uk Dr Geoff Butcher, Babraham Institute, Babraham, Cambridge, UK

Details zur Ausgabe

• Verlag: IRL Press
• Erscheinungsdatum: 1997
• Sprache: Englisch
• ISBN 10: 0199635536
• ISBN 13: 9780199635535
• Einband: Taschenbuch
• Anzahl der Seiten: 240
• Herausgeber: Fernandez Nelson, Butcher Geoff
• Kontakt zum Hersteller: ORIGINAL KAISER; https://corp.oup.com/; ; Via Liguria 4; San Giuliano Milanese ; MI; 20098; Italien