Autisms: Molecules to Model Systems - Hardcover

Hardcover

ISBN 10: 0199744319 ISBN 13: 9780199744312

Verlag: OXFORD UNIV PR, 2012

Inhaltsangabe

This book focuses on tractable genetic finding in autism and dissects the underlying neurobiology which helps understand the pathophysiology of the disorder, ultimately leading to identifying novel treatments

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Über die Autorin bzw. den Autor

Craig M. Powell, M.D., Ph.D. is a Neurologist and Neuroscientist interested in the molecular, cellular, and circuit-level mechanisms underlying cognitive function and cognitive dysfunction in disorders such as autism and intellectual disability. Dr. Powell has been integrally involved in understanding brain abnormalities in genetic animal models of autism based on mutations in autism-associated genes such as SHANK3, neuroligins, neurexins, and PTEN. His work integrates multiple approaches to understanding how genetic mutations lead to altered neuronal function and altered circuit function to cause the behavioral symptoms of autism. His work has identified potential therapeutic targets for autism using such models.



Lisa M. Monteggia, PhD is the Ginny and John Eulich Professor in Autism Spectrum Disorders, and Associate Professor of Psychiatry, at University of Texas Southwestern Medical Center in Dallas. Dr. Monteggia's research interests focus on the molecular and cellular basis of neural plasticity as it pertains to psychiatric disorders. She utilizes molecular, cellular, behavioral, biochemical and electrophysiological approaches to elucidate how specific genes may contribute to psychiatric disorders in animal models, specifically focusing on better understanding Rett Syndrome/Autism and depression. Once these mechanisms are understood, treatments can be developed to target specific molecular pathways for therapeutic advances.

Details zur Ausgabe

• Verlag: OXFORD UNIV PR
• Erscheinungsdatum: 2012
• Sprache: Englisch
• ISBN 10: 0199744319
• ISBN 13: 9780199744312
• Einband: Gebundene Ausgabe
• Auflage: 1
• Anzahl der Seiten: 420
• Herausgeber: Powell Craig M., Monteggia Lisa M.
• Kontakt zum Hersteller: Nicht verfügbar
• Verantwortliche Person: Nicht verfügbar