Following the successful format of the first volume on long- term potentiation -- aleading candidate for the neuronal basis of learning and memory -- Volume 2 brings together the mostrecent data and hypotheses by top neuroscientists regarding the mechanisms of this phenomenon and oflong-term depression (LTD).The book is divided into several sections covering different aspects ofthe field ranging from molecular mechanisms of plasticity to computational neurobiology. It revisitssome of the major points covered in Volume 1, updating them in this fast-moving field. It alsointroduces several new issues that have arisen since then. Of the many possible new topics thatcould have been added, the editors have focused on retrograde messengers and the mechanisms andfunctions of LTP and LTD because they are the subject of much interest, research, and controversy.The section on retrograde messengers deals primarily with nitric oxide.
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