Excerpt from A System of Medicine, Vol. 5
Blood-supply. - The blood-supply of the liver is of a peculiarly rich character, being a double one; it flows partly through the portal vein, partly through the hepatic artery. Both these vessels enter the liver through its transverse fissure, and along with the biliary ducts their branches occupy the portal cs throughout the liver.
The branches of the portal vein ramify between the lobules (inter lobular) and end in a capillary network within the lobule itself. Within the portal cs the branches of the portal vein receive small veins returning the blood distributed by the hepatic artery.
The hepatic artery is distributed (a) to the walls of the ducts and vessels and the surrounding connective tissue of the portal cs; (b) to the capsule of the liver; and (c) it finally breaks up bet ween the lobules, supplying blood to the walls of the interlobular blood-vessels and the bile-ducts. Whether it transmits any blood directly to the lobule seems to be doubtful.
Within the lobule the capillary network is of the closest description, the capillaries being separated from one another by intervals commonly not larger than the diameter of two liver-cells. In the centre of each lobule the blood is collected into the central (intralobular) branches of the hepatic vein, which in turn collect and form larger branches (sublobular); these in turn merge into the large venous trunks of the hepatic vein, which finally opens into the inferior vena cava. Throughout their course the branches Of the hepatic vein are distinguished by the thinness of their walls.
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