Cell Activation and Apoptosis in HIV Infection: Implications for Pathogenesis and Therapy (Advances in Experimental Medicine and Biology) - Hardcover

Hardcover

ISBN 10: 0306450631 ISBN 13: 9780306450631

Verlag: Springer, 1995

Inhaltsangabe

T-Cell/Macrophage Activation and HIV Infection.- 1. CD4+ and CD8+ T Lymphocyte Activation in HIV Infection: Implications for Immune Pathogenesis and Therapy.- 2. Markers of Immune Cell Activation and Disease Progression: Cell Activation in HIV Disease.- 3. The Role of the Cell Cycle in HIV-1 Infection.- 4. Molecular Basis of Cell Cycle Dependent HIV-1 Replication: Implications for Control of Virus Burden.- 5. Regulation of Macrophage Activation and HIV Replication.- 6. Investigations on Autologous T-Cells for Adoptive Immunotherapy of AIDS.- 7. Rational Problems Associated with the Development of Cellular Approaches in Controlling HIV Spread.- Apoptosis and Viropathogenesis of HIV Disease.- 8. The Role of Surface CD4 in HIV-Induced Apoptosis.- 9. Mechanism of Apoptosis in Peripheral Blood Mononuclear Cells of HIV-Infected Patients.- 10. Programmed Death of T Cells in the Course of HIV Infection.- 11. T Cell Apoptosis as a Consequence of Chronic Activation of the Immune System in HIV Infection.- 12. Apoptosis during HIV Infection: A Cytopathic Effect of HIV or an Important Host-Defense Mechanism against Viruses in General?.- Apoptosis and Immunopathogenesis of HIV Disease.- 13. From Cell Activation to Cell Depletion: The Programmed Cell Death Hypothesis of AIDS Pathogenesis.- 14. Immunosuppression by a Noncytolytic Virus Via T Cell Mediated Immunopathology: Implication for AIDS.- 15. Clonal Expansion of T Cells and HIV Genotypes in Microdissected Splenic White Pulps Indicates Viral Replication in Situ and Infiltration of HIV-Specific Cytotoxic T Lymphocytes.- 16. Autoimmunity, Apoptosis Defects, and Retroviruses.- 17. AIDS as Immune System Activation: Key Questions that Remain.- Mediators of T-Cell Activation/Apoptosis and Therapeutic Applications.- 18. Inhibition of T Lymphocyte Activation and Apoptotic Cell Death by Cyclosporin A and Tacrolimus (FK506): Its Relevance to Therapy of HIV Infection.- 19. Cyclophilin and Gag in HIV-1 Replication and Pathogenesis.- 20. Long-Term Follow-up of HIV Positive Asymptomatic Patients Having Received Cyclosporin A.- 21. Prospective Views of HIV Pathology: Clues for Therapeutic Strategies.

Details zur Ausgabe

• Verlag: Springer
• Erscheinungsdatum: 1995
• Sprache: Englisch
• ISBN 10: 0306450631
• ISBN 13: 9780306450631
• Einband: Gebundene Ausgabe
• Anzahl der Seiten: 245
• Herausgeber: Andrieu Jean-Marie, Lu Wei
• Kontakt zum Hersteller: Springer Heidelberg; buchhandel-buch@springer.com; ; Tiergartenstr. 17; Heidelberg; 69121; Deutschland