Resolving the Antibiotic Paradox: Progress in Understanding Drug Resistance and Development of New Antibiotics: v. 456 (Advances in Experimental Medicine and Biology) - Hardcover

 
9780306460395: Resolving the Antibiotic Paradox: Progress in Understanding Drug Resistance and Development of New Antibiotics: v. 456 (Advances in Experimental Medicine and Biology)
Hardcover
ISBN 10: 0306460394 ISBN 13: 9780306460395
Verlag: Springer, 1999

Inhaltsangabe

1. Antibiotic Resistance: The Big Picture; D. Mazel, J. Davies. 2. Clinical impact of Antibiotic Resistance; S.A. Lerner. 3. Reversing Tetracycline Resistance: A Renaissance for the Tetracycline Family of Antibiotics; S.B. Levy, M. Nelson. 4. Aminoglycoside Antibiotics: Structures, Functions, and Resistance; G.D. Wright, et al. 5. How beta-Lactamases have Driven Pharmaceutical Drug Discovery; From Mechanistic Knowledge to Clinical Circumvention; K. Bush, S. Mobashery. 6. Antifolate Resistance Mechanisms from Bacteria to Cancer Cells with Emphasis on Parasites; M. Ouellette, et al. 7. Resistance to Antitubercular Drugs; L.A. Basso, J.S. Blanchard. 8. Structure and Function of Multidrug Transporters; H.W. van Veen, W.N. Konings. 9. Metalloid Resistance Mechanisms; R. Mukhopadhyay, et al. 10. The Impact of Bacterial Genomics on Antibacterial Discovery; D.J.C. Knowles, F. King. 11. Peptidoglycan Biosynthesis: Unexploited Antibacterial Targets within a Familiar Pathway; K.K. Wong, D.L. Pompliano. 12. Design, Synthesis, and Evaluation of Novel Oxazolidinone Antibacterial Agents Active against Multidrug-Resistant Bacteria; M.R. Barbachyn, et al. 13. Concept, Design, and Preclinical Evaluation of Quinolonyl Lactam Antibacterials; P.M. Hershberger, T.P. Demuth Jr. 14. Bacterial Two-Component Signalling as a Therapeutic Target in Drug Design: Inhibition of NRII by the Diphenolic Methanes (Bisphenols); J.M. Domagala, et al. Index.

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Reseña del editor

The title of this proceedings comes from the book "The Antibiotic Paradox" by Stuart B. Levy, referring to the paradox that the more antibiotics are used to treat infectious diseases, the less effective they become. When antibiotics were first introduced, they were considered wonder drugs because they were so effective. But with time bacteria have become resistant to nearly all antibiotics, and resistance is spreading faster than new antibiotics are being developed. This book identifies the issues concerning resistance, as well as describing efforts to develop new drugs that overcome the problem of resistance.

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Verlag
Springer
Erscheinungsdatum
1999
Sprache
Englisch
ISBN 10 
0306460394
ISBN 13 
9780306460395
Einband
Tapa dura
Anzahl der Seiten
308
Herausgeber
Rosen Barry P., Mobashery Shahriar
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
CMN Printpool Inh. Mathis Neumann
https://www.also.com/ec/cms5/en_6000/6000/index.jsp

Friedrich-Karl-Str. 9
Hamburg
Deutschland

Weitere beliebte Ausgaben desselben Titels

9781461372202: Resolving the Antibiotic Paradox: Progress in Understanding Drug Resistance and Development of New Antibiotics: 456 (Advances in Experimental Medicine and Biology)

Vorgestellte Ausgabe

ISBN 10:  1461372208 ISBN 13:  9781461372202
Verlag: Springer, 2012
Softcover