Bioactive Components of Human Milk: 501 (Advances in Experimental Medicine and Biology) - Hardcover

Newburg, David S.; International Society For Research On Hu

Hardcover

ISBN 10: 0306466538 ISBN 13: 9780306466533

Verlag: Springer, 2001

Inhaltsangabe

Although breast-feeding has long been associated with lowered infant morbid­ ity and mortality from infectious disease, until relatively recently little was known regarding the individual components of human milk aside from their nutritive func­ tions and the presence of secretory antibodies. Over the last 40 years, and especially over the last decade, evidence has been growing that human milk contains a large number of materials that are bioactive and that are not found in artificially formu­ latedinfantdiets. Disparatelinesofresearcharecurrentlyproducingsurprisinglylong listsofnewlyrecognizedhumanmilkcomponents-antimicrobialsand immunomod­ ulators, includinganti-inflammatoryagents, antioxidants, cytokines, andhormones­ with biological activities that relate to pathogenesis, inflammation, development, metabolic regulation, and other functions. The sum of all of these biologically active milk components may account for the strong protection that human milk affords nursing infants. Strictly speaking, most components of human milk could be considered bioac­ tive, since nutrients are bioactive by definition. A major emphasis of this book, how­ ever, is on defining what is known about components of human milk that inhibit common pathogens of the infant, those that have hormonal and/or cytokine activity, those that have immunomodulatory and/or anti-inflammatory activity, xenobiotics, and nutrients that are uniquely essential to early development. The topic of bioactive substances in human milk was explored in depth at the th 8 International Conference of the International Society for Research on Human Milk and Lactation (ISRHML) held at Plymouth, Massachusetts, October 25-29, 1997. This book contains the proceedings of that conference.

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Reseña del editor

The major emphasis in this book is a compilation and definition of what is known about components of human milk, including glycoconjugates, that inhibit common pathogens of the infant. Also discussed are other bioactive constituents whose relevant biological roles are also beginning to be defined. Hormonal and cytokine activity, immunomodulating and autoinflammatory agents, xenobiotics, and conditionally essential nutrients in milk could have roles in the protection of the infant, but may also participate in digestive processes, maternal-infant communication, maturation of the gut, central nervous system, and other components of infant growth and development. Like the protective activities, these are discussed in terms of their presence in milk, structures, potential functions, and structure/function relationship. Components whose role is nutritional support during early development of the infant are also included.

Details zur Ausgabe

• Verlag: Springer
• Erscheinungsdatum: 2001
• Sprache: Englisch
• ISBN 10: 0306466538
• ISBN 13: 9780306466533
• Einband: Tapa dura
• Anzahl der Seiten: 616
• Herausgeber: Newburg David S.
• Kontakt zum Hersteller: Nicht verfügbar
• Verantwortliche Person: CMN Printpool Inh. Mathis Neumann; https://www.also.com/ec/cms5/en_6000/6000/index.jsp; ; Friedrich-Karl-Str. 9; Hamburg; Deutschland