Review of Dod's Approach to Deriving an Occupational Exposure Level for Trichloroethylene (The National Academies of Sciences Engineering Medicine: Consensus Study) - Softcover

National Academies Of Sciences Engineeri; Division On Earth And Life Studies; Board On Environmental Studies And Toxic

Softcover

ISBN 10: 0309499240 ISBN 13: 9780309499248

Verlag: NATL ACADEMY PR, 2020

Inhaltsangabe

Trichloroethylene (TCE) is a solvent that is used as a degreasing agent, a chemical intermediate in refrigerant manufacture, and a component of spot removers and adhesives. It is produced in mass quantities but creates dangerous vapors and is an environmental contaminant at many industrial and government facilities, including facilities run by the U.S. Department of Defense (DoD). It is important to determine the safe occupational exposure level (OEL) for the solvent in order to protect the health of workers who are exposed to its vapors. However, there are concerns that the current occupational standards insufficiently protect workers from these health threats.

Review of DOD's Approach to Deriving an Occupational Exposure Level for Trichloroethylene makes recommendations to improve the DoD's approach to developing an OEL for TCE, strengthen transparency of the process, and improve confidence in the final OEL value. This report reviews the DoD's approach using a literature review, evidence synthesis based on weight of evidence [WOE], point-of-departure derivation, physiologically based pharmacokinetic modeling, extrapolation tools, and explores other elements of the process of deriving an OEL for TCE. It examines scientific approaches to developing exposure values and cancer risk levels, defining the scope of the problem, and improving hazard identification.

Details zur Ausgabe

• Verlag: NATL ACADEMY PR
• Erscheinungsdatum: 2020
• Sprache: Englisch
• ISBN 10: 0309499240
• ISBN 13: 9780309499248
• Einband: Taschenbuch
• Anzahl der Seiten: 70
• Kontakt zum Hersteller: Nicht verfügbar
• Verantwortliche Person: Nicht verfügbar