Multimodal Biomarkers for Central Nervous System Disorders: Development, Validation, and Clinical Integration: Proceedings of a Workshop - Softcover

National Academies Of Sciences, Engineering, And Medicine; Health And Medicine Division; Board On Health Sciences Policy; Forum On Neuroscience And Nervous System Disorders

Softcover

ISBN 10: 0309708478 ISBN 13: 9780309708470

Verlag: National Academies Press, 2023

Inhaltsangabe

A key step towards reducing the burden of central nervous system (CNS) disorders is the identification of disease-specific biomarkers that can help predict, monitor, and guide treatment development. Recent technological advances have led to an increased number of biomarkers for different CNS disorders, providing the opportunity to generate multimodal biomarkers. While multimodal biomarkers can serve as promising tools to better diagnose and make accurate disease assessments, there remain challenges in current data collection, standardization, and validation practices that impede in their development. Recognizing the need for increased CNS biomarker integration, the National Academies Forum on Neuroscience and Nervous System Disorders hosted a public workshop in March 2023 to explore steps toward this goal, including data collection for biomarker discovery, development, validation, and assessment of clinical utility. This Proceedings of a Workshop summarizes the discussions held during the workshop.

Table of Contents

• Front Matter
• 1 Introduction and Background
• 2 Multimodal Biomarkers for Central Nervous System Disorders
• 3 Exploring the State of the Science of Multimodal Biomarkers for Central Nervous System Disorders
• 4 Opportunities for Precision Medicine
• 5 Standardization and Methodology for Multimodal Biomarkers
• 6 Regulatory Decision Making
• 7 Exploring Opportunities to Move Forward
• Appendix A: References
• Appendix B: Agenda

Details zur Ausgabe

• Verlag: National Academies Press
• Erscheinungsdatum: 2023
• Sprache: Englisch
• ISBN 10: 0309708478
• ISBN 13: 9780309708470
• Einband: Tapa blanda
• Anzahl der Seiten: 82
• Herausgeber: Norris Sheena M. Posey, Childers Eva, Carter Sarah
• Kontakt zum Hersteller: Nicht verfügbar
• Verantwortliche Person: Nicht verfügbar