Many hereditary cancer syndromes are linked to alterations in single genes. Detection and clinical interpretation of these alterations can guide cancer risk reduction for patients and their families through screening, prophylactic measures, and other strategies. Diagnosis and Management of Hereditary Cancer summarizes hereditary syndromes and their associated cancers and genes. The information is presented in 50 practice-enhancing tables that relate clinical, genetic, diagnostic, and management aspects in a manner that has previously not been available in a single reference. Intended to guide the specialist as well the novice, this volume will elevate the care of hereditary cancer patients and their families.
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Dr. Henson is director of the Hereditary Cancer Clinic at the Georgia Cancer Center, Medical College of Georgia, Augusta University, in Augusta, Georgia, USA. He has practiced neuro-oncology for over 25 years and is a well-published leader in several related fields, with over 125 papers and book chapters. He attended the Intensive Course in Cancer Genomic Risk Assessment at City of Hope in 2018. He was previously Chief of Oncology Services at Piedmont Healthcare and on the staff of Massachusetts General Hospital and the faculty of Harvard Medical School for 17 years. Dr. Henson is a member of numerous societies, including as an affiliate member of the American College of Medical Genetics.
Mr. Resta is a retired cancer genetic counselor with 37 years of experience in the Swedish Hereditary Cancer Clinic. He is a well-known expert in this field with over 60 publications. He has published extensively on the historical, ethical, and psychological aspects of genetic counseling. He is a former Editor-in-Chief of the Journal of Genetic Counseling and a frequent contributor to The DNA Exchange, the most widely read genetic counseling blog. He is the 2013 recipient of the Natalie Weissberger Paul National Achievement Award, the most distinguished honor within the National Society of Genetic Counselors.
There are a number of hereditary cancers whose formation can be ascribed to a single gene, which unlike most types of cancers can be used for cancer risk reduction and early detection. Diagnosis and Management of Hereditary Cancer summarizes these and presents for readers the field of brain cancer genetics in a series of 50 tables. These tables each organize known research from different initial observations, to help best diagnose. Clinicians can use symptoms to extrapolate to specific conditions and associated genes, or begin with genes to connect with common symptoms and disorders. Together these diagnostic methods when met in daily clinical practice will allow clinicians to identify the possibility of a hereditary condition. Information organized in this way is not presently available in a single reference until now. This volume will elevate the care of hereditary cancer patients with practice-enhancing information and enhance development of the field by stimulating better diagnosis, management, and treatment.
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