Statistics in Human Genetics (Arnold Applications of Statistics S.) - Softcover

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9780340662410: Statistics in Human Genetics (Arnold Applications of Statistics S.)
Softcover
ISBN 10: 0340662417 ISBN 13: 9780340662410
Verlag: Hodder Arnold, 1997

Inhaltsangabe

In human genetic research, sophisticated statistical methods are increasingly being used to analyse results. Until now there has been no book to introduce and explain these methods. The methods are based on both biology and statistics and are likely to contribute to major scientific and medical advances in the next century. Topics include the estimation of allele frequencies, the testing for Hardy-Weinberg equilibrium, classical and complex segregation analysis, linkage analysis for Mendelian and complex diseases and quantitative traits, the detection of allelic associations, the estimation of heritability for multifactorial traits and path analysis. An understanding of elementary statistical concepts is assumed, but the objectives, principles and limitations of the methods are discussed in detail. The book will interest scientists engaged in human genetic research and advanced students of genetics and statistics.

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In human genetic research sophisticated statistical methods are increasingly being used to analyse results. Until now there has been no book to introduce and explain these methods. The methods are based on both biology and statistics and are likely to contribute to major scientific and medical advances in the next century. Topics include the estimation of allele frequencies, the testing for Hardy-Weinberg equilibrium, classical and complex segregation analysis, linkage analysis for Mendelian and complex diseases and quantitative traits, the detection of allelic associations, the estimation of heritability for multifactorial traits and path analysis. An understanding of elementary statistical concepts is assumed, but the objectives, principles and limitations of the methods are discussed in detail.

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Verlag
Hodder Arnold
Erscheinungsdatum
1997
Sprache
Englisch
ISBN 10 
0340662417
ISBN 13 
9780340662410
Einband
Tapa blanda
Anzahl der Seiten
304
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
Nicht verfügbar

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