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Excerpt from A Biochemical Study of the Toxin of Bacillus Pyocyaneus<br/><br/>The physiological properties of the toxin of Bacillus pyocyaneus have been most often studied on the tissues of mammalian, warm-blooded animals. In this study the action of this toxin upon an animal of the cold-blooded type-paramoecium-was investigated. The object was to ascertain the general protoplasmic reaction to the toxin rather than that of any Specialized group of cells. This purpose was still further favored by the selection of a highly generalized form of protoplasm, that of a free-living unicellular organism. Furthermore a successful effort was made to produce a toxin of constant i. E. Of easily reproducible properties. A satisfactory method was sought for raising the bacterial cultures and especially of separating the characteristic toxin from.other toxic chemical products of the bacillus. The comparability of different stocks of toxin thus prepared by the same method was further increased by the measurement of the strength of the toxin against the same practically uniform standard consisting of paramoecia raised by a con stant method.
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A Biochemical Study of the Toxin of Bacillus Pyocyaneus: Thesis
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Paperback. Zustand: New. Print on Demand. This book presents an intriguing examination of the toxin produced by Bacillus pyocyaneus, conducted via the lens of paramoecium, a cold-blooded protozoan. A comprehensive examination of the Pyocyaneus toxin's physiological characteristics is established through this avenue. Historical context is introduced by way of established research. In this context, the author thoroughly describes their methodology for growing B. pyocyaneus cultures and isolating their characteristic toxin. They further establish a method for testing toxin effects on paramoecia, utilizing a novel salt solution and discussing potential hematological effects and immunization possibilities. Thematic depth is achieved through a discussion of the chemical structure of the toxin, its impact on paramoecia, and the remarkable ability of paramoecia to detoxify the toxin over time. The author discovers that this detoxification process may be linked to reduced oxidative abilities in toxin-exposed paramoecia. Crucially, this book highlights the significance of the paramoecium model in understanding the general protoplasmic reaction to toxins. This approach provides unique insights into the physiological processes of diverse organisms, bacteria and protozoa alike. It also raises potential research avenues for understanding the role of specific cell receptors in toxin resistance and the relationship between oxidative processes and toxin effects. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item. Bestandsnummer des Verkäufers 9780365901334_0
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A Biochemical Study of the Toxin of Bacillus Pyocyaneus
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A Biochemical Study of the Toxin of Bacillus Pyocyaneus
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