This book, the first volume in the new Green Syntheses series, presents reaction pathways that include a single reaction or a multi-step sequence to a known product. A unique feature of this series is to include green metrics as a key component of submissions of original works in order to substantiate the level of "greenness" of new chemical processes. It helps fill an expressed need by both academia and industry to incorporate, together with accurate synthetic protocols, metrics analysis as a means to rigorously define efficiency and sustainability of chemical syntheses.
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John Andraos earned a PhD in 1992 from the University of Toronto in physical organic chemistry. He has done consulting assignments with the pharmaceutical industry on various aspects of synthesis optimization and green chemistry education, including Merck, Bioverdant, Scientific Update, Apotex Pharmaceuticals, and Row2 Technologies. Dr. Andraos is the author of 50 scientific papers in refereed journals, 8 book chapters on the subject of green chemistry metrics and education, and the book The Algebra of Organic Synthesis: Green Metrics, Design Strategy, Route Selection, and Optimization (CRC Press/Taylor & Francis, 2012). In 2000 he launched the CareerChem website (http://www.careerchem.com/MainFrame.html), and he is now a full-time consultant with CareerChem in Toronto, Canada.
Pietro Tundo is professor of organic chemistry at Ca' Foscari University of Venice (Italy). He is holder of the Unesco Chair on Green Chemistry (UNTWIN No. 731) and author of approximately 260 scientific publications and 30 patents. He authored the book Continuous Flow Methods in Organic Synthesis (E. Horwood, Chichester, UK, 1991) and is editor of approximately 15 books. Dr. Tundo was president of the Organic and Biomolecular Chemistry Division of IUPAC (biennium 2007-2009) and presently is chairman of the Working Party on Green and Sustainable Chemistry of the European Association for Chemical and Molecular Sciences (EuCheMS). He is founder of the IUPAC International Conferences Series on Green Chemistry.
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