The Kinetochore:: From Molecular Discoveries to Cancer Therapy - Hardcover

 
9780387690735: The Kinetochore:: From Molecular Discoveries to Cancer Therapy
Hardcover
ISBN 10: 0387690735 ISBN 13: 9780387690735
Verlag: Springer, 2008

Inhaltsangabe

Kinetochores orchestrate the faithful transmission of chromosomes from one generation to the next. Kinetochores were first depicted over 100 years ago, but kinetochore research has progressed by leaps and bounds since the first description of their constituent DNA and proteins in the 1980s. “The Kinetochore: from Molecular Discoveries to Cancer Therapy” presents a thorough up-to-date analysis of kinetochore and centromere composition, formation, regulation, and activity, both in mitosis and meiosis, in humans and “model” eukaryotic species, and at natural and mutant neocentromeres. Recently initiated translational research on kinetochores is also discussed as kinetochores are being mined as a very rich target for the next generations of anti-cancer drugs.

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Von der hinteren Coverseite

Kinetochores orchestrate the faithful transmission of chromosomes from one generation to the next. Kinetochores were first depicted over 100 years ago, but kinetochore research has progressed by leaps and bounds since the first description of their constituent DNA and proteins in the 1980s. "The Kinetochore: from Molecular Discoveries to Cancer Therapy" edited by Peter De Wulf and William C. Earnshaw presents a thorough up-to-date analysis of kinetochore and centromere composition, formation, regulation, and activity, both in mitosis and meiosis, in humans and "model" eukaryotic species, and at natural and mutant neocentromeres. Recently initiated translational research on kinetochores is also discussed as kinetochores are being mined as a very rich target for the next generations of anti-cancer drugs.

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Verlag
Springer
Erscheinungsdatum
2008
Sprache
Englisch
ISBN 10 
0387690735
ISBN 13 
9780387690735
Einband
Gebundene Ausgabe
Auflage
1
Anzahl der Seiten
529
Herausgeber
De Wulf Peter, Earnshaw William
Kontakt zum Hersteller
Springer Nature Customer Service Center GmbH
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Europaplatz 3
Heidelberg
69115
Deutschland

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Vorgestellte Ausgabe

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