NMR Spectroscopy in Pharmaceutical Analysis - Hardcover

Hardcover

ISBN 10: 0444531734 ISBN 13: 9780444531735

Verlag: Elsevier Science, 2008

Inhaltsangabe

For almost a decade, quantitative NMR spectroscopy (qNMR) has been established as valuable tool in drug analysis. In all disciplines, i. e. drug identification, impurity profiling and assay, qNMR can be utilized.
Separation techniques such as high performance liquid chromatography, gas chromatography, super fluid chromatography and capillary electrophoresis techniques, govern the purity evaluation of drugs. However, these techniques are not always able to solve the analytical problems often resulting in insufficient methods. Nevertheless such methods find their way into international pharmacopoeias. Thus, the aim of the book is to describe the possibilities of qNMR in pharmaceutical analysis.
Beside the introduction to the physical fundamentals and techniques the principles of the application in drug analysis are described: quality evaluation of drugs, polymer characterization, natural products and corresponding reference compounds, metabolism, and solid phase NMR spectroscopy for the characterization drug substances, e.g. the water content, polymorphism, and drug formulations, e.g. tablets, powders. This part is accompanied by more special chapters dealing with representative examples. They give more detailed information by means of concrete examples.

Details zur Ausgabe

• Verlag: Elsevier Science
• Erscheinungsdatum: 2008
• Sprache: Englisch
• ISBN 10: 0444531734
• ISBN 13: 9780444531735
• Einband: Gebundene Ausgabe
• Anzahl der Seiten: 528
• Herausgeber: Holzgrabe Ulrike, Wawer Iwona, Diehl Bernd
• Kontakt zum Hersteller: Elsevier Health Science; tradeorders@elsevier.com; ; London Wall 125; London; EC2Y 5AS; Vereinigtes Königreich
• Verantwortliche Person: gpsr@libri.de; gpsr@libri.de; ; Europaallee 1; Bad Hersfeld; 36244; Deutschland