Design and Optimization in Organic Synthesis (Volume 8) (Data Handling in Science and Technology, Volume 8) - Hardcover

Carlson, R.

 
9780444892010: Design and Optimization in Organic Synthesis (Volume 8) (Data Handling in Science and Technology, Volume 8)

Inhaltsangabe

This is the first general textbook on experimental design and optimization in organic synthesis. The book presents a unified methodology for carrying out systematic studies when the objective is to develop efficient and optimum synthetic methods. Strategies are included both for exploring the experimental conditions and for systematic studies of entire reaction systems (substrates, reagent(s) and solvents). The methodology is based on multivariate statistical techniques. The following topics are treated in depth: classical two-level designs for screening experiments, gradient methods (steepest ascent, simplex methods) as well as response surface techniques for optimization, principal components analysis and PLS modelling.The book is intended as a hands-on text for chemists and engineers engaged in developing synthetic methods in industrial research, e.g. in fine chemicals and pharmaceuticals production, as well as for advanced undergraduate students, graduate students, and researchers in an academic environment.

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Reseña del editor

This is the first general textbook on experimental design and optimization in organic synthesis. The book presents a unified methodology for carrying out systematic studies when the objective is to develop efficient and optimum synthetic methods. Strategies are included both for exploring the experimental conditions and for systematic studies of entire reaction systems (substrates, reagent(s) and solvents). The methodology is based on multivariate statistical techniques. The following topics are treated in depth: classical two-level designs for screening experiments, gradient methods (steepest ascent, simplex methods) as well as response surface techniques for optimization, principal components analysis and PLS modelling. The book is intended as a hands-on text for chemists and engineers engaged in developing synthetic methods in industrial research, e.g. in fine chemicals and pharmaceuticals production, as well as for advanced undergraduate students, graduate students, and researchers in an academic environment.

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Weitere beliebte Ausgaben desselben Titels

9780444515278: Design and Optimization in Organic Synthesis: Second Revised and Enlarged Edition (Volume 24) (Data Handling in Science and Technology, Volume 24)

Vorgestellte Ausgabe

ISBN 10:  0444515275 ISBN 13:  9780444515278
Verlag: Elsevier Science Ltd, 2005
Hardcover