This text introduces the major methods of creating carbon-carbon and carbon-nitrogen bonds, along with functional group interconversions (oxidation, reduction, halogenation). The use of protective groups and solid-phase methods is also discussed.
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James R. Hanson is Professor in the Department of Chemistry at the University of Sussex.
Synthesis is one of the major endeavours of the organic chemist, and the design of a successful synthesis requires a sound knowledge of functional group chemistry, stereochemistry and organic reaction mechanisms.
Organic Synthetic Methods introduces the major methods of creating carbon-carbon and carbon-nitrogen bonds, along with functional group interconversions (Oxidation, reduction, halogenation). The use of protecting groups and solid-phase methods are also discussed. The analysis of the structure of a target molecule, in terms of the structural consequences of synthetic reactions, is introduced to enable the student to identify key dissections and building blocks and hence develop a suitable synthetic method. Examples of the synthesis of labelled compounds are also provided.
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