This unique book presents a systematic review of the methods for the determination of binding constants of complex formation in solution. Collects material that has been scattered throughout the literature of several separate fields. Offered here are methods from the areas of acid-base chemistry, metal-ion coordination compounds, hydrogen-bonding, charge-transfer complexation, hydrophobic interaction, and protein-binding. Discusses the relevant thermodynamics, modelling, statistics and regression analysis, and interpretation of data. Includes fresh discussions of random association (contact complexes), selection of standard states, and comparison of results. Treats all of the experimental methods useful for measuring these equilibrium constants, including those based on spectrophotometry, nuclear magnetic resonance, reaction kinetics, potentiometry, solubility, liquid-liquid partitioning, dialysis, chromatography, flourimetry, and many others.
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Kenneth Connors is Professor in the School of Pharmacy at the University of Wisconsin at Madison.
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hardcover. Zustand: Good. Hardcover ex-library with typical marks shows moderate cover wear. No jacket. Text is unmarked. Ships FAST! Bestandsnummer des Verkäufers 2510250079
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Zustand: Good. Good in a Very Good dust jacket; Hardcover; Dust jacket is clean and glossy with no tears, and has not been price-clipped; Very light wear to the boards with "straight" edge-corners; Clean textblock edges; Handwriting/notes to about 35 pages, otherwise the endpapers and all text pages are clean and unmarked; The binding is excellent with a straight spine; This book will be shipped in a sturdy cardboard box with foam padding; Medium Format (8.5" - 9.75" tall); White, blue, and brown dust jacket with title in brown lettering; 1987, Wiley-Interscience Publishing; 432 pages; "Binding Constants: The Measurement of Molecular Complex Stability," by Kenneth A. Connors. Bestandsnummer des Verkäufers SKU-107BC04310171
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Hardcover. Zustand: new. Hardcover. This unique book presents a systematic review of the methods for the determination of binding constants of complex formation in solution. Collects material that has been scattered throughout the literature of several separate fields. Offered here are methods from the areas of acid-base chemistry, metal-ion coordination compounds, hydrogen-bonding, charge-transfer complexation, hydrophobic interaction, and protein-binding. Discusses the relevant thermodynamics, modelling, statistics and regression analysis, and interpretation of data. Includes fresh discussions of random association (contact complexes), selection of standard states, and comparison of results. Treats all of the experimental methods useful for measuring these equilibrium constants, including those based on spectrophotometry, nuclear magnetic resonance, reaction kinetics, potentiometry, solubility, liquid-liquid partitioning, dialysis, chromatography, flourimetry, and many others. This unique book presents a systematic review of the methods for the determination of binding constants of complex formation in solution. Collects material that has been scattered throughout the literature of several separate fields. Shipping may be from multiple locations in the US or from the UK, depending on stock availability. Bestandsnummer des Verkäufers 9780471830832