Variation in the Human Genome (Ciba Foundation Symposia) - Hardcover

Symposium On Variation In The Human Genome (1995 Ciba Foundation)

Hardcover

ISBN 10: 0471961523 ISBN 13: 9780471961529

Verlag: John Wiley & Sons Ltd, 1996

Inhaltsangabe

The mapping of human genes is proceeding rapidly. Genes associated with specific inherited diseases are being identified, often providing insight into the molecular cause of the disease. At the moment, however, little consideration is being given to the variation present in different human populations. Variation in the Human Genome discusses methods of analysing population genetic data and how contemporary genetic heterogeneity arises during the evolution and migration of human populations. Specific disorders such as cystic fibrosis, beta-thalassaemia, fragile X, phenylketonuria and tumour development susceptibility are used to illustrate this genetic variability and mechanisms of gene mutation and evolution.

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The mapping of human genes is proceeding rapidly, and genes associated with specific inherited diseases are being identified, often providing insight into the molecular cause of the disease. At the moment, however, little consideration is being given to the variation present in different human populations. This variation bears a record of the population history of our species and how this has been affected by diseases, ecological adaptations, and pharmacological and nutritional responses. Treatment of inherited diseases that involve several genes will require knowledge of the degree and nature of genetic variation present in a population. This book discusses methods of analysing population genetic data and how contemporary genetic heterogeneity arises during the evolution and migration of human populations. Specific disorders ? such as cystic fibrosis, ß-thalassaemia, fragile X, phenylketonuria and tumour development susceptibility ? are used to illustrate this genetic variability and mechanisms of gene mutation and evolution.

Details zur Ausgabe

• Verlag: John Wiley & Sons Ltd
• Erscheinungsdatum: 1996
• Sprache: Englisch
• ISBN 10: 0471961523
• ISBN 13: 9780471961529
• Einband: Gebundene Ausgabe
• Anzahl der Seiten: 329
• Herausgeber: Chadwick Derek, Cardew Gail
• Kontakt zum Hersteller: Nicht verfügbar
• Verantwortliche Person: Nicht verfügbar