"Huge applause... women have always been in science—despite those who would pretend otherwise.” --Bonnie Garmus, New York Times bestselling author of Lessons in Chemistry
She gave up everything — and changed the world.
A riveting novel based on the true story of the woman who stopped a pandemic, from the bestselling author of Mrs. Poe.
In 1940s and ’50s America, polio is as dreaded as the atomic bomb. No one’s life is untouched by this disease that kills or paralyzes its victims, particularly children. Outbreaks of the virus across the country regularly put American cities in lockdown. Some of the world’s best minds are engaged in the race to find a vaccine. The man who succeeds will be a god.
But Dorothy Horstmann is not focused on beating her colleagues to the vaccine. She just wants the world to have a cure. Applying the same determination that lifted her from a humble background as the daughter of immigrants, to becoming a doctor –often the only woman in the room--she hunts down the monster where it lurks: in the blood.
This discovery of hers, and an error by a competitor, catapults her closest colleague to a lead in the race. When his chance to win comes on a worldwide scale, she is asked to sink or validate his vaccine—and to decide what is forgivable, and how much should be sacrificed, in pursuit of the cure.
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Lynn Cullen grew up in Fort Wayne, Indiana, and is the bestselling author of The Sisters of Summit Avenue, Twain’s End, and Mrs. Poe, which was named an NPR 2013 Great Read and an Indie Next List selection. She lives in Atlanta with her husband, their dog, and two unscrupulous cats.
1
Nashville, Tennessee, 1941
Say, Horstmann, want to meet a jerk?"
The voice seeped into the melee in which Dorothy, a modern-day Gulliver, was being roped down by tiny little men. Apparently, she'd stumbled into the little guys' mysterious world, and they were hopping mad.
She peeled open an eye. In front of the cardboard boxes in the storeroom where the residents liked to steal a nap, a baby-faced redheaded man was peering down the front of his white gown at her. Probably not a dream. Barry Montgomery was a resident at Vanderbilt, same as she. But she wasn't sure. She'd slept thirty minutes over the last forty-eight hours-not uncommon these past ten months at Vandy-and her senses couldn't be trusted.
She shut her stinging eye. "Do I?"
"Oh, I think you'll want to meet this one, if the nurses are any indication."
Over the radio that Dorothy forgot she'd turned on, the sound of clacking typewriters announced the end of orchestral music and the start of a news program. She pushed herself upright and snapped off the receiver.
"Don't you want to hear the news?" Barry had a newborn baby and two kids, but with his carroty cowlick and ruddy cheeks, he looked like he should be carrying a slingshot and harmonica in his pocket, not tongue depressors and an otoscope. He was thirty, a year older than she was-did she look so young? "What country do you think the Germans are invading today?"
Even half-asleep, unease slithered into her gut. On another side of the planet, horrible things were happening, yet they were carrying on here in the States as if this were not so. This was not sustainable. "Are there any more countries in Europe left for them to occupy?"
"Russia." Barry's stethoscope bounced against his white gown as he pulled her to her feet. "Upsy daisy! Come get a look at this character-if you can see him through the wall of panting nurses."
"I can't believe I'm giving up precious sleep for this."
"Yeah, yeah. You can thank me later."
Her dream hadn't quite left her as Barry prodded her down the hall. It must have come from studying Group A streptococcus under a microscope earlier. What robust lives bacteria lived! When they found themselves in a favorable new situation, like a plate of blood agar, the happy little hedonists rejoiced at their good luck and threw themselves into a frenzy of feasting, after which they procreated, then procreated some more, until there was nothing left to squeeze out of life and then they died. She was almost fond of the tiny terrors, so bold, so hungry, so hell-bent on having it all. She would have been fond of them, had they not claimed millions of human lives.
An ominous mechanical whoooooossshhh-GROAN, whoooooossshhh-GROAN broke into her thoughts. Behind the windows of the polio ward, nurses could be seen rushing between toddlers crying in their cribs and kids laid out in full-body casts. Other nurses tended to the source of the metallic moaning, the ventilators containing individual children.
In medical school, Dorothy had asked, once, to be put into an "iron lung," to see how it felt. A tall teenage patient had just graduated to a cuirass respirator, the kind that fits on the patient's chest, and had vacated his extra-long chamber model. Two nurses hesitantly agreed to Dorothy's request, glancing at each other when she laid herself down on a gurney.
"Transfer me in!" she'd said. A crinolined lady taking a picnic to watch the first battle of the Civil War could have been no more jovial.
The nurses wheeled her next to the ventilator and, in a real-life Gulliver's Travels situation, heaved her up from the stretcher and dropped her onto a cushioned tray. They then slid the tray into the tank and closed the coffin-like lid, latching it shut with just her head jutting out.
"Ready!"
Someone turned it on. With a clank and a groan, the machine wound up. Pressure bore down on Dorothy's chest as if an elephant had sat on it. Then, after every scrap of breath was flattened out of her, the elephant got up; a tsunami of oxygen rushed in. She was drowning in air when the elephant plumped down again, vacuuming it out of her.
She pounded the sides of the tank. From somewhere in her lungs, she scraped together the wind to gasp. "Help!"
The nurse-Dorothy still remembered her name, Trudy-put her face inches from Dorothy's, her breath smelling of the Wrigley's tucked between teeth and cheek. "Go along with it. Let go. Let the machine do the work."
"I can't!"
Dorothy felt a hand grab hers-Trudy had reached into one of the portholes. "Yes, you can."
Humiliatingly near tears, Dorothy let the device squeeze out the air left in her and then push in new oxygen. She breathed, not on her terms, not comfortably, not naturally, not happily, but she breathed.
Even now, that fear still felt fresh as she scanned the row of machines, the mirror positioned over the end of each reflecting the terror, bewilderment, or resignation of the child within. Her job as a doctor was to fix these broken kids. Worse, they actually thought she could.
Barry plucked at her arm. "Come on, Horstmann. You're not going to beat polio today."
"What if I do someday?"
He laughed. "Sure you will. And I'm finding the Fountain of Youth."
Down the corridor, a crowd had formed at the nurses' station. The man in the center didn't seem much older than she was. He was almost comically handsome, with a matinee idol's dark hair oiled in waves and a dapper mustache. He even had a Laurence Olivier-like cleft in his chin. Judging from his expensive pin-striped suit, he could have actually been a celebrity, or else he came from money. Most people in her profession had money in their background, at least they did at the upper-echelon medical schools. Women were scarce in a place such as this; women from families like hers, even scarcer. In fact, she had so far yet to meet another person like herself in her field. She was the human equivalent of a unicorn.
Barry addressed him over the nurses. "Doctor, I'd like you to meet somebody."
The nurses, seeing that a physician was speaking, even if only a resident, cleared a path for Barry.
"Excuse me." Dorothy tried to get through, too, but the nurses were not conditioned to falling aside for a woman. "Sorry. Sorry." She squeezed a nurse's arm in apology after knocking into her, then held out her hand to Young Dr. Suave. "I'm Dorothy Horstmann. Nice to meet you."
He stopped talking long enough for his gaze to travel the considerable distance up and down her doctor's gown. She braced herself. Go ahead. Say it.
He put out his hand. "Dr. Horstmann, nice to meet you. Albert Sabin. This is my colleague"-he ushered forward the young man next to him-"Robbie Ward."
Dr. Ward, as big-boned and brawny as a football player, pulled back his chin to gawk at her. "You are tall!"
Ah, there it was. Somehow, seeing a six-foot-one woman pressed a lever in most people's brains, and those three words instantly shot out. It was uncanny.
He shook his head in appreciation. "You are a lot of blonde."
She supposed the bird's nest atop her head qualified her as a blonde. She smiled for Dr. Ward, not wanting him to be embarrassed should he realize how idiotic he sounded, then turned to Dr. Sabin. "Aren't you the one who advised doctors not to perform tonsillectomies in the summer because of their connection to polio?"
He bowed. "I am."
"How old were you when you wrote that paper?" Barry asked. "Ten?"
"Twenty-six," Dr. Sabin said. "But even a ten-year-old could have suspected that performing surgery in polio season might be a bad idea." He crooked a corner of his mouth. "More often than not, the obvious is true, yet we ignore it."
Oh, yes. He was that Dr. Sabin, the boy wonder. She'd...
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