Presenting a balance between science and clinical relevance, this text is a concise overview of immunology for students. Focusing on what medical students need to know, it aims to be a reader-friendly, patient-oriented text in this challenging field. Experimental detail is kept to a minimum, used only where it helps the student understand difficult concepts. The text has clinical boxes with real patient scenarios, and also provides a review of major components in immunological interaction: important molecules, specific immune response and role of innate response in complementing specific response, and immunity to microbes. Integrating overviews are presented to ensure that the most common failing of immunology teaching - how all the components interact - hoice questions focus the student on the core content which is critical for understanding and progress in the medical curriculum. The text also includes clinical boxes, which place immunology in a clinical context, and technical boxes, which relate immunology to common diagnostic techniques.
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Dr Nairn has taught immunology to medical students since 1981, first at the University of Michigan Medical School and, since 1995, at Creighton University School of Medicine. He has participated in developing curricula and in school-wide curriculum revision, leading the biannual workshop on Teaching Microbiology and Immunology to Medical Students sponsored by the Association of Medical School M & I Chairs for the last six years.
Dr Nairn trained in the UK obtaining his PhD at the University of London and National Institute for Medical Research, Mill Hill, London. His research interests have included MHC antigen structure and function, antigen processing, cell activation in the inflammatory response etc. His laboratory has been funded by theNational Institute of Health, American Cancer Society etc, and he is the author of numerous peer-reviewed articles, chapters and reviews in immunology and related research areas. In addition to research in immunology, Dr Nairn hascollaborated in research studies in medical education, particularly with respect to case based learning.
Matthew Helbert is a Consultant Clinical Immunologist and Honorary Senior Lecturer at St Bartholomew's Hospital London. He runs a primary immunodeficiency clinical service and so has regular contact with patients. In addition, he runs a diagnostic laboratory. He is involved in teaching to undergraduate medical students and in training specialist registrars. He has a special interest in immunological memory.
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