Growth Factors and Their Receptors in Cancer Metastasis: 2 (Cancer Metastasis - Biology and Treatment, 2) - Hardcover

Matsumoto, Kunio; Nakamura, Toshikazu; Jiang, Wen G.

 
9780792371410: Growth Factors and Their Receptors in Cancer Metastasis: 2 (Cancer Metastasis - Biology and Treatment, 2)
Hardcover
ISBN 10: 0792371410 ISBN 13: 9780792371410
Verlag: Springer, 2001

Inhaltsangabe

about the involvement of signaling Transforming growth factor in tumor development and metastasis. plays a central role in the signaling network that controls morphogenesis, 2. THE BASICS OF growth and cell differentiation in SIGNALING multicellular organisms. The different members of this pleiotropic family of 2. 1. receptor signaling growth and differentiation factors seem to The family of growth factors regulate many processes in human disease consists of more than thirty members in and, in particular, tumor development. humans alone (15, 16). They cluster in Our understanding of how two major groups, the group composed of initiated signals are mediated has both the bone morphogenetic proteins increased dramatically in the last fifteen (BMP) and growth and differentiation years. Firstly, the prototype of factors (GDFs), and the group formed by this still constantly growing family, was the Activins, and Nodals. The two identified and cloned (1). Secondly, the groups differ in their use of receptors for family receptors were transmembrane receptors and the identified by expression cloning from subsequent activation of the mammalian tissue culture (2-7). Thirdly, transcriptional mediators (for recent genetic screens in Drosophila reviews see (13, 14, 17)).

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Reseña del editor

about the involvement of signaling Transforming growth factor in tumor development and metastasis. plays a central role in the signaling network that controls morphogenesis, 2. THE BASICS OF growth and cell differentiation in SIGNALING multicellular organisms. The different members of this pleiotropic family of 2. 1. receptor signaling growth and differentiation factors seem to The family of growth factors regulate many processes in human disease consists of more than thirty members in and, in particular, tumor development. humans alone (15, 16). They cluster in Our understanding of how two major groups, the group composed of initiated signals are mediated has both the bone morphogenetic proteins increased dramatically in the last fifteen (BMP) and growth and differentiation years. Firstly, the prototype of factors (GDFs), and the group formed by this still constantly growing family, was the Activins, and Nodals. The two identified and cloned (1). Secondly, the groups differ in their use of receptors for family receptors were transmembrane receptors and the identified by expression cloning from subsequent activation of the mammalian tissue culture (2-7). Thirdly, transcriptional mediators (for recent genetic screens in Drosophila reviews see (13, 14, 17)).

Reseña del editor

This text provides knowledge of growth factors and their receptors in cancer metastasis. It covers basic cellular and molecular biology of growth factors and their receptors, as well as their role in cancer and cancer metastasis in clinical settings. The book is intended for cancer biologists, cell biologists, geneticists, oncologists, surgeons and physicians. It is also a reference for those who work in the area of cancer research, cancer therapies, cancer care, the pharmaceutical industry, as well as postgraduates and undergraduates.

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Verlag
Springer
Erscheinungsdatum
2001
Sprache
Englisch
ISBN 10 
0792371410
ISBN 13 
9780792371410
Einband
Tapa dura
Anzahl der Seiten
316
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
CMN Printpool Inh. Mathis Neumann
https://www.also.com/ec/cms5/en_6000/6000/index.jsp

Friedrich-Karl-Str. 9
Hamburg
Deutschland

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9789048157570: Growth Factors and their Receptors in Cancer Metastasis: 2 (Cancer Metastasis - Biology and Treatment)

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