Non-Myeloablative Allogeneic Transplantation: 110 (Cancer Treatment and Research) - Hardcover

Bashey, Asad; Ball, Edward D.

Hardcover

ISBN 10: 0792376463 ISBN 13: 9780792376460

Verlag: Springer, 2002

Inhaltsangabe

Non-myeloablative allogeneic stem cell transplantation (also known as mini-transplantation or reduced-intensity conditioning transplantation) is a major advance in the field of hematopoietic transplantation within the last 5 years. This approach uses non-cytotoxic or reduced-intensity cytotoxic therapy to prepare patients for allografting of hematopoietic stem cells and lymphocytes. It has the potential to deliver the potent anti-tumor immunotherapy and bone marrow replacement capacity of allogeneic stem cell transplantation to patients with reduced treatment-related morbidity and mortality. It may also enable allogeneic transplantation in patients who would be considered ineligible for conventional transplants because of co-morbidity or advanced age. However, this approach may necessitate more careful monitoring of post-transplant chimerism and malignant disease-status than is usual with conventional allografting. There is also controversy regarding the best preparative regimen and graft-versus-host disease prophylaxis to use.

Details zur Ausgabe

• Verlag: Springer
• Erscheinungsdatum: 2002
• Sprache: Englisch
• ISBN 10: 0792376463
• ISBN 13: 9780792376460
• Einband: Tapa dura
• Anzahl der Seiten: 232
• Herausgeber: Bashey M. D. Ph. D. Asad
• Kontakt zum Hersteller: Nicht verfügbar
• Verantwortliche Person: Nicht verfügbar