Retinoids: Progress in Research and Clinical Applications (CLINICAL DERMATOLOGY, Band 5) - Hardcover

Hardcover

ISBN 10: 0824787587 ISBN 13: 9780824787585

Verlag: CRC Press Inc, 1993

Inhaltsangabe

This volume contains papers presented at the Conference on Retinoids: New Trends in Research and Clinical Applications, held in 1991 in Palermo, Italy, describing the latest research findings on biochemistry, nutrition, molecular and cell biology and developmental biology, as well as the pharmacology and the therapeutic use of vitamin A and its congeners.;Written by leading authorities in the field from the USA, Europe and Japan, Retinoids, amongst other things: addresses retinol-supported retinoic acid (RA) synthesis and catabolism; identifies synthetic ligands with a high selective affinity for RAR-alpha, -beta and -gamma nuclear receptors, determining if they would show pharmacological properties similar to the natural parent substance all-trans RA; considers the embryonic/foetal cellular retinoid-binding proteins and evidence for their participation in normal and abnormal morphogenesis; discusses a novel arotinoid, Ro 40-8757, that exhibited improved anti-tumour efficacy and safety in pre-clinical tests; and reports the audioradiographic distribution of retinol and RA in organs of pregnant hamsters and foetuses.

Details zur Ausgabe

• Verlag: CRC Press Inc
• Erscheinungsdatum: 1993
• Sprache: Englisch
• ISBN 10: 0824787587
• ISBN 13: 9780824787585
• Einband: Gebundene Ausgabe
• Anzahl der Seiten: 672
• Herausgeber: Livrea Maria A., Packer Lester
• Kontakt zum Hersteller: Nicht verfügbar
• Verantwortliche Person: Nicht verfügbar