Structure-Based Drug Design - Hardcover

Hardcover

ISBN 10: 0824798694 ISBN 13: 9780824798697

Verlag: CRC Press Inc, 1997

Inhaltsangabe

Introducing the most recent advances in crystallography, nuclear magnetic resonance, molecular modeling techniques, and computational combinatorial chemistry, this unique, interdisciplinary reference explains the application of three-dimensional structural information in the design of pharmaceutical drugs. Furnishing authoritative analyses by world-renowned experts, Structure-Based Drug Design discusses protein structure-based design in optimizing HIV protease inhibitors and details the biochemical, genetic, and clinical data on HIV-1 reverse transcriptase presents recent results on the high-resolution three-dimensional structure of the catalytic core domain of HIV-1 integrase as a foundation for divergent combination therapy focuses on structure-based design strategies for uncovering receptor antagonists to treat inflammatory diseases demonstrates a systematic approach to the design of inhibitory compounds in cancer treatment reviews current knowledge on the Interleukin-1 (IL-1) system and progress in the development of IL-1 modulators describes the influence of structure-based methods in designing capsid-binding inhibitors for relief of the common cold and much more!

Über diesen Titel

Über die Autorin bzw. den Autor

Pandi Veerapandian

Details zur Ausgabe

• Verlag: CRC Press Inc
• Erscheinungsdatum: 1997
• Sprache: Englisch
• ISBN 10: 0824798694
• ISBN 13: 9780824798697
• Einband: Gebundene Ausgabe
• Auflage: 1
• Anzahl der Seiten: 647
• Herausgeber: Veerapandian Pandi
• Kontakt zum Hersteller: Nicht verfügbar
• Verantwortliche Person: Taylor & Francis Verlag GmbH; GPSR@taylorandfrancis.com; ; Kaufingerstraße 24, 80331 München, Germany; München; Deutschland