This text examines the effects of acute and chronic exercise on the metabolism of cyclic AMP and protein kinase in cardiac and skeletal muscle. It also presents information gained during more than 20 years' work in the Soviet Union. Arranged in three parts, the study first provides a comprehensive review of the role of phosphorylation in the functional regulation of cardiac and skeletal muscle. In the second part, it presents information describing the effects of exercise on cAMP and cAMP-dependent protein kinase. The final part gives a summary of this information.
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