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Generation and Interpretation of Morphogen Gradients: A Subject Collection from Cold Spring Harbor Perspectives in Biology (Cold Spring Harbor Laboratory) - Hardcover

Briscoe, James

 
9780879698812: Generation and Interpretation of Morphogen Gradients: A Subject Collection from Cold Spring Harbor Perspectives in Biology (Cold Spring Harbor Laboratory)
Hardcover
ISBN 10: 0879698810 ISBN 13: 9780879698812
Verlag: Cold Spring Harbor Laboratory Press, 2010

Inhaltsangabe

Signaling by diffusible morphogens, such as Hedgehog, Wingless, TGF-ß, and various growth factors, is essential during embryogenesis. The establishment of concentration gradients of these morphogens is vital for developmental patterning, ensuring that distinct differentiated cell types appear in the right place and at the right time in forming tissues.

Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology explores how morphogen gradients are generated and interpreted during development. The contributors examine the regulation of morphogen synthesis, trafficking, and diffusion, as well as the complex webs of signaling mechanisms and transcriptional responses in recipient cells --whose fates are dictated by these morphogens. Including discussion of the roles of morphogen gradients in various tissues in organisms from yeast to humans, the volume is a vital reference for developmental biologists and cell biologists wishing to know how cell fate is determined during embryogenesis.

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Verlag
Cold Spring Harbor Laboratory Press
Erscheinungsdatum
2010
Sprache
Englisch
ISBN 10 
0879698810
ISBN 13 
9780879698812
Einband
Gebundene Ausgabe
Auflage
1
Anzahl der Seiten
308
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Verantwortliche Person
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