The Nucleus: A Subject Collection from Cold Spring Harbor Perspectives in Biology - Hardcover

 
9780879698942: The Nucleus: A Subject Collection from Cold Spring Harbor Perspectives in Biology
Hardcover
ISBN 10: 0879698942 ISBN 13: 9780879698942
Verlag: Cold Spring Harbor Laboratory Press,U.S., 2010

Inhaltsangabe

The nucleus of a cell contains its DNA and is the site where DNA replication, transcription, and RNA processing take place. Nuclei have many domains but lack the membrane-bound organelles characteristic of the cytoplasm. Instead, nuclear bodies appear to dynamically self-organize, assembling and disassembling according to the functional demands of the cell.Written and edited by experts in the field, this volume includes contributions discussing the relationship between nuclear structure and function, the various nuclear bodies that have been identified, and the organization of the nuclear lamina and nuclear pore complex. Other contributions examine the higher-order organization of chromatin within the nucleus and the dynamics of DNA replication, transcription, DNA repair, and RNA transport.Including a historical introduction to the field and discussion of the numerous pathological conditions involving disruption of nuclear structure and function, this volume is essential reading for all molecular and cell biologists, as well as pathologists interested in the role of nuclear architecture in disease.

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Über die Autorin bzw. den Autor

Tom Misteli, National Cancer Institute; David L. Spector, Cold Spring Harbor Laboratory

Von der hinteren Coverseite

The nucleus of a cell contains its DNA and is the site where DNA replication, transcription, and RNA processing take place. Nuclei have many domains but lack the membrane-bound organelles characteristic of the cytoplasm. Instead, nuclear bodies appear to dynamically self-organize, assembling and disassembling according to the functional demands of the cell.Written and edited by experts in the field, this volume includes contributions discussing the relationship between nuclear structure and function, the various nuclear bodies that have been identified, and the organization of the nuclear lamina and nuclear pore complex. Other contributions examine the higher-order organization of chromatin within the nucleus and the dynamics of DNA replication, transcription, DNA repair, and RNA transport.Including a historical introduction to the field and discussion of the numerous pathological conditions involving disruption of nuclear structure and function, this volume is essential reading for all molecular and cell biologists, as well as pathologists interested in the role of nuclear architecture in disease.

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Verlag
Cold Spring Harbor Laboratory Press,U.S.
Erscheinungsdatum
2010
Sprache
Englisch
ISBN 10 
0879698942
ISBN 13 
9780879698942
Einband
Gebundene Ausgabe
Anzahl der Seiten
517
Herausgeber
Mistelli Tom, Spector David L.
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
Nicht verfügbar