Trace Amines: Comparative and Clinical Neurobiology (Experimental and Clinical Neuroscience) - Hardcover

Hardcover

ISBN 10: 0896031446 ISBN 13: 9780896031449

Verlag: Humana, 1988

Inhaltsangabe

This is the third Proceedings book to arise from biennial conferen ces on the Trace Amines. Since our first meeting in 1983 in Edmonton, Canada, progress has been brisk and, as will be seen from the ensuing pages, it is now possible to include major contributions from inverte brate neurobiologists as well as receptorologists. In the opening ses sion we heard about the distribution of the trace amines-now clear ly a misnomer-in insects and the pharmacological, receptor, and syn aptic characteristics of octopamine and tryptamine as well as the pos sibility of monoamines in general being targets for insecticide discov ery. In mammalian brain the distribution and characterization of the tryptamine receptor has proceeded to the point where two types have been described as well as novel agonists and antagonists, and, for the first time, a binding site for p-tyramine has been described. The com bination of lesions and pharmacological and metabolic manipulations now permits the mapping of trace aminergic pathways, and the rap idly accumulating evidence from releasing drugs, in situ microdialy sis, iontophoresis, and second messenger systems lends credence to the claim that the trace amines possess neuromodulatory functions.

Details zur Ausgabe

• Verlag: Humana
• Erscheinungsdatum: 1988
• Sprache: Englisch
• ISBN 10: 0896031446
• ISBN 13: 9780896031449
• Einband: Gebundene Ausgabe
• Anzahl der Seiten: 496
• Herausgeber: Boulton Alan A., Juorio A. V., Downer R. G. H.
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