Modeling Inhibitors of Matrix Metalloproteinases (QSAR in Environmental and Health Sciences) - Hardcover

Jha, Tarun

Hardcover

ISBN 10: 1032289260 ISBN 13: 9781032289267

Verlag: CRC Press, 2023

Inhaltsangabe

Matrix metalloproteinases (MMPs) have been established as promising biomolecular targets for novel drug design and discovery against numerous major disease conditions including various cancers, cardiovascular, neurodegenerative, inflammatory diseases, and more. This book covers various modern molecular modeling methodologies particularly related to MMP inhibitors. Included in the text are descriptions of ligand-based drug designing and structure-based drug designing modeling strategies for designing potential and target specific or selective MMPIs. This book will benefit those who are looking for an in-depth text on the design and discovery processes of novel and selective MMPIs.

Features

• Describes modeling strategies applied to MMPs
• Elaborates on the designing strategies of MMPs specifically
• Includes in-depth analyses of related case studies
• Acts as a guide for medicinal chemists, not only from pharmaceutical industries, but also from academia
• Covers various modern molecular modeling methodologies, particularly related to MMPIs

Über diesen Titel

Über die Autorin bzw. den Autor

Tarun Jha is the senior most Professor of the Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India. He has already supervised 20 Ph.D. students and is guiding 4 more for that. He also guided 6 post-doctoral fellows and completed 9 research projects. He has published 200 research articles and 10 book chapters as well as jointly edited a book. Prof. Jha is one of the Editorial Board Members of the journal 'SAR and QSAR in Environmental Research' published by Taylor and Francis. He is also serving as a reviewer of 26 internationally reputed journals. His research area includes the design, synthesis, and biological evaluation of anticancer small molecules, especially inhibitors of zinc-dependent metalloenzymes.

Details zur Ausgabe

• Verlag: CRC Press
• Erscheinungsdatum: 2023
• Sprache: Englisch
• ISBN 10: 1032289260
• ISBN 13: 9781032289267
• Einband: Gebundene Ausgabe
• Auflage: 1
• Anzahl der Seiten: 474
• Kontakt zum Hersteller: preigu GmbH & Co. KG; mail@preigu.de; ; Lengericher Landstr. 19; Osnabrück; Niedersachsen; 49078; Deutschland