Chromatin Accessibility: Methods and Protocols (Methods in Molecular Biology, 2611, Band 2611) - Hardcover

Buch 237 von 381: Methods in Molecular Biology
 
9781071628980: Chromatin Accessibility: Methods and Protocols (Methods in Molecular Biology, 2611, Band 2611)
Hardcover
ISBN 10: 1071628984 ISBN 13: 9781071628980
Verlag: Humana, 2023

Inhaltsangabe

This detailed volume provides a comprehensive resource covering the existing and state-of-the-art tools in the field of profiling chromatin accessibility and its dynamics. Beginning with a section on bulk-cell methods for profiling chromatin accessibility and nucleosome positioning that rely on enzymatic cleavage of accessible DNA and produce information about relative accessibility, the book continues with methods that use single-molecule and enzymatic approaches to solving the problem of mapping absolute occupancy/accessibility, emerging tools for mapping DNA accessibility and nucleosome positioning in single cells, imaging-based methods for visualizing accessible chromatin in its nuclear context, as well as computational methods for the processing and analysis of chromatin accessibility datasets. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 


Authoritative and up-to-date, Chromatin Accessibility: Methods and Protocols serves as an extensive and useful reference for researchers studying different facets of chromatin accessibility in a wide variety of biological contexts. 

Chapter 6 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Die Inhaltsangabe kann sich auf eine andere Ausgabe dieses Titels beziehen.

Von der hinteren Coverseite

This detailed volume provides a comprehensive resource covering the existing and state-of-the-art tools in the field of profiling chromatin accessibility and its dynamics. Beginning with a section on bulk-cell methods for profiling chromatin accessibility and nucleosome positioning that rely on enzymatic cleavage of accessible DNA and produce information about relative accessibility, the book continues with methods that use single-molecule and enzymatic approaches to solving the problem of mapping absolute occupancy/accessibility, emerging tools for mapping DNA accessibility and nucleosome positioning in single cells, imaging-based methods for visualizing accessible chromatin in its nuclear context, as well as computational methods for the processing and analysis of chromatin accessibility datasets. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 


Authoritative and up-to-date, Chromatin Accessibility: Methods and Protocols serves as an extensive and useful reference for researchers studying different facets of chromatin accessibility in a wide variety of biological contexts. 

Chapter 6 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

„Über diesen Titel“ kann sich auf eine andere Ausgabe dieses Titels beziehen.

Verlag
Humana
Erscheinungsdatum
2023
Sprache
Englisch
ISBN 10 
1071628984
ISBN 13 
9781071628980
Einband
Gebundene Ausgabe
Auflage
1
Anzahl der Seiten
352
Herausgeber
Marinov Georgi K., Greenleaf William J.
Kontakt zum Hersteller
preigu GmbH & Co. KG
mail@preigu.de

Lengericher Landstr. 19
Osnabrück
Niedersachsen
49078
Deutschland

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9781071629017: Chromatin Accessibility: Methods and Protocols (Methods in Molecular Biology, Band 2611)

Vorgestellte Ausgabe

ISBN 10:  1071629018 ISBN 13:  9781071629017
Verlag: Humana, 2024
Softcover