Cerebrospinal Fluid (CSF) Proteomics: Methods and Protocols (Methods in Molecular Biology, 2914, Band 2914) - Hardcover

Hardcover

ISBN 10: 1071644610 ISBN 13: 9781071644614

Verlag: Humana, 2025

Inhaltsangabe

This fully updated book explores cerebrospinal fluid (CSF) molecular profiles in normal and pathological states, with a focus on mass spectrometry and different protein methods currently used in neurobiological disciplines. The book includes CSF sample preparation methods, shotgun and targeted proteomic workflows, as well as methods to characterize specific posttranslational modifications to achieve finer molecular resolution in proteomic studies of CSF. Additional chapters delve into experimental -omics strategies applied to the CSF lipidome and metabolome, as well as bioinformatic pipelines useful for analyzing and integrating the molecular information derived from high-throughput -omics experiments. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 

 

Authoritative and up-to-date, Cerebrospinal Fluid (CSF) Proteomics: Methods and Protocols, Second Edition serves as an ideal resource for researchers beginning their journey into CSF molecular profiles, as well as for established researchers seeking valuable insight into the growing utility of proteomics and metabolomics in neuroscience.

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This fully updated book explores cerebrospinal fluid (CSF) molecular profiles in normal and pathological states, with a focus on mass spectrometry and different protein methods currently used in neurobiological disciplines. The book includes CSF sample preparation methods, shotgun and targeted proteomic workflows, as well as methods to characterize specific posttranslational modifications to achieve finer molecular resolution in proteomic studies of CSF. Additional chapters delve into experimental -omics strategies applied to the CSF lipidome and metabolome, as well as bioinformatic pipelines useful for analyzing and integrating the molecular information derived from high-throughput -omics experiments. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 

 

Authoritative and up-to-date, Cerebrospinal Fluid (CSF) Proteomics: Methods and Protocols, Second Edition serves as an ideal resource for researchers beginning their journey into CSF molecular profiles, as well as for established researchers seeking valuable insight into the growing utility of proteomics and metabolomics in neuroscience.

Details zur Ausgabe

• Verlag: Humana
• Erscheinungsdatum: 2025
• Sprache: Englisch
• ISBN 10: 1071644610
• ISBN 13: 9781071644614
• Einband: Gebundene Ausgabe
• Auflage: 2
• Anzahl der Seiten: 349
• Herausgeber: Santamaría Enrique, Fernández-Irigoyen Joaquín
• Kontakt zum Hersteller: ROXIO; https://www.also.com/ec/cms5/en_6000/6000/index.jsp; ; Friedrich-Karl-Str. 9; Hamburg; 22391; Deutschland