Protein Moonlighting in Biology and Medicine - Hardcover

Henderson, Brian; Fares, Mario A.; Martin, Andrew C. R.

Hardcover

ISBN 10: 1118952081 ISBN 13: 9781118952085

Verlag: Wiley-Blackwell, 2016

Inhaltsangabe

THE PAST 25 YEARS HAS SEEN THE EMERGENCE OF A WEALTH OF DATA SUGGESTING THAT NOVEL BIOLOGICAL FUNCTIONS OF KNOWN PROTEINS PLAY IMPORTANT ROLES IN BIOLOGY AND MEDICINE.  THIS ABILITY OF PROTEINS TO EXHIBIT MORE THAN ONE UNIQUE BIOLOGICAL ACTIVITY IS KNOWN AS PROTEIN MOONLIGHTING. MOONLIGHTING PROTEINS CAN EXHIBIT NOVEL BIOLOGICAL FUNCTIONS, THUS EXTENDING THE FUNCTION OF THE PROTEOME, AND ARE ALSO IMPLICATED IN THE PATHOLOGY OF A GROWING NUMBER OF IDIOPATHIC AND INFECTIOUS DISEASES.  THIS BOOK, WRITTEN BY A CELL BIOLOGIST, PROTEIN EVOLUTIONARY BIOLOGIST AND PROTEIN BIOINFORMATICIAN, BRINGS TOGETHER THE LATEST INFORMATION ON THE STRUCTURE, EVOLUTION AND BIOLOGICAL FUNCTION OF THE GROWING NUMBERS OF MOONLIGHTING PROTEINS THAT HAVE BEEN IDENTIFIED, AND THEIR ROLES IN HUMAN HEALTH AND DISEASE.  THIS INFORMATION IS REVEALING THE ENORMOUS IMPORTANCE PROTEIN MOONLIGHTING PLAYS IN THE MAINTENANCE OF HUMAN HEALTH AND IN THE INDUCTION OF DISEASE PATHOLOGY.  PROTEIN MOONLIGHTING IN BIOLOGY AND MEDICINE WILL BE OF INTEREST TO A GENERAL READERSHIP IN THE BIOLOGICAL AND BIOMEDICAL RESEARCH COMMUNITY.

Über diesen Titel

Críticas:

'The "Protein Moonlighting in Biology and Medicine" book presents a very well-designed, comprehensive account of the basic knowledge and practical aspects of moonlighting proteins that have been culminating over the last two decades. Written by a cell biologist teaming up with two protein evolution and bioinformatics experts, this title provides a very useful digestible read on the structure, function, evolution, and bioinformatics of moonlighting proteins. Readers are oriented to these topics by two relevant introductory chapters. The book also addresses the diverse involvement of moonlighting proteins in cell biology, health maintenance, and idiopathic and infectious diseases. A very useful feature in this book, which is not frequently considered in other multi-authored titles, is the authors' effort to present a coherent story by bridging chapters together incorporating an 'introduction' section at the beginning of each one. It is a very useful, contemporary book for students and researchers in biology, biomedicine and protein science.' Science Progress, 100:4 (2017)

Reseña del editor:

The past 25 years has seen the emergence of a wealth of data suggesting that novel biological functions of known proteins play important roles in biology and medicine. This ability of proteins to exhibit more than one unique biological activity is known as protein moonlighting. Moonlighting proteins can exhibit novel biological functions, thus extending the function of the proteome, and are also implicated in the pathology of a growing number of idiopathic and infectious diseases. This book, written by a cell biologist, protein evolutionary biologist and protein bioinformatician, brings together the latest information on the structure, evolution and biological function of the growing numbers of moonlighting proteins that have been identified, and their roles in human health and disease. This information is revealing the enormous importance protein moonlighting plays in the maintenance of human health and in the induction of disease pathology. Protein Moonlighting in Biology and Medicine will be of interest to a general readership in the biological and biomedical research community.

Über diese Auflage

• Verlag: Wiley-Blackwell
• Erscheinungsdatum: 2016
• ISBN 10: 1118952081
• ISBN 13: 9781118952085
• Einband: Tapa dura
• Anzahl der Seiten: 328