Excerpt from The Opsonic Method of Treatment: A Short Compendium for General Practitioners, Students, and Others
Pasteur carried on the work initiated by Jenner, and endeavoured in divers directions to induce a prophylaxis by the inoculation, mostly in an attenuated form, of the bacterial agents themselves or products derived from them.
Koch, in 1890, however, was the first to attempt the cure of an infection by a specific remedy - viz, of tuberculosis by means of tuberculin. Unfortunately, doses far in excess of those now employed were used, with the result that tuberculin fell into grave disrepute.
Denys and Leclef immunized rabbits against strepto cocci, and showed that the resultant increased phago cytosis was due not to any changes in the Ieucocytes, but to an alteration in the serum they demonstrated that the leucocytes of the immunized animal, when placed in normal serum, showed no greater phagocytic activity than did normal leucocytes.
The studies of Leishman on phagocytosis paved the way for the discoveries of Wright upon the bactericidal agents present in the blood, and in especial of the one to which he gave the name of opsonin.' Having devised a means of accurately estimating the opsonic content of the blood, he was thereby enabled to learn the reason of the previous failures of tuberculin, more or less to obviate the attendant danger, and place the Opsonic method of treatment of tuberculosis upon a scientific basis.
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Paperback. Zustand: New. Print on Demand. This book provides a comprehensive overview of the origins of vaccine therapy and the development of its contemporary practice as opsonic treatment. The author traces the genesis of the field back to Jenner's work on smallpox in the 18th century and how subsequent discoveries by the author and other scientists led to the development of the science of vaccine therapy. The author explores the nature and complexity of the immune response to bacterial infection, especially the intricate relationship between white blood cells and bacteria, and explores the therapeutic possibilities opened up by understanding the role of opsonins, which act as intermediaries between the two. The author argues that vaccines that stimulate the immune system can be more effective than direct treatment of bacterial infection, and presents the scientific evidence to support its use. The book provides a detailed guide to the practical application of opsonic treatment backed up by case studies and the author's own experience treating infections. It is written in a clear and concise style with a depth of scientific explanation that makes it accessible to the layperson with an interest in the field. This book will appeal to medical professionals seeking to learn more about the history and practice of vaccine therapy, and anybody looking to broaden their knowledge of immunology and its applications. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item. Bestandsnummer des Verkäufers 9781330065426_0
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PAP. Zustand: New. New Book. Shipped from UK. Established seller since 2000. Bestandsnummer des Verkäufers LW-9781330065426
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PAP. Zustand: New. New Book. Shipped from UK. Established seller since 2000. Bestandsnummer des Verkäufers LW-9781330065426
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