Excerpt from The Journal of Experimental Medicine, Vol. 34: December 1, 1921; Studies on the Treatment of Human Trypanosomiasis With Tryparsamide (the Sodium Salt of N-Phenylglycineamide-P-Arsonic Acid)
It is Obvious that any extended application of a new remedy for administration in human beings must be preceded by a careful study of its action in relatively few patients irrespective of the scope of the initial investigations in the laboratory. In a problem such as the therapy Oi human trypanosomiasis as just indicated, it is of the utmost importance to ascertain such fundamental facts as the initial speed of therapeutic activity Of various sized single doses, as measured by the length of time required to clear the superficial lymph glands and blood of trypanosomes and the permanency of this effect; the action Of the drug, if any, in the advanced stages Of the disease as indicated by examination Of the Spinal fluid and the mental and nervous response of the patient; the general physical reaction of the patient as shown by weight Observations, blood counts, etc.; and finally, the determina tion of any untoward observable effects. On the basis of a series of such facts obtained in a certain number Of patients, a rational system Of therapeutic procedure can then be logically attempted.
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Paperback. Zustand: New. Print on Demand. This book presents the groundbreaking work of The Rockefeller Institute for Medical Research and their study of experimental treatments for diseases caused by protozoan infections. The author, an esteemed medical researcher, led a mission to the Belgian Congo to study the effects of a newly developed drug on patients suffering from African sleeping sickness caused by Trypanosoma gambiense. This detailed report shares the results of treating 77 native cases of trypanosomiasis using varying dosages of the drug. This book provides valuable insights into the initial speed of therapeutic activity of single doses, as measured by the length of time required to clear the lymph glands and blood of the trypanosomes. The author explores the permanency of this effect and examines the general physical reactions of the patients and any adverse effects. The author's observations were made under typical field conditions, highlighting the practical implications of treating patients in remote areas. The research in this book contributes to a growing body of knowledge on the treatment of human trypanosomiasis, providing a significant historical reference for medical researchers and practitioners dedicated to combating this devastating disease. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item. Bestandsnummer des Verkäufers 9781331018308_0
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PAP. Zustand: New. New Book. Shipped from UK. Established seller since 2000. Bestandsnummer des Verkäufers LW-9781331018308
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