Practical Biotransformations: A Beginner's Guide (Postgraduate Chemistry Series) - Softcover

Grogan, Gideon

Softcover

ISBN 10: 1405171251 ISBN 13: 9781405171250

Verlag: Wiley-Blackwell, 2009

Inhaltsangabe

The development of new asymmetric catalytic methods is of fundamental importance to industrial synthetic chemistry. The demand for optically pure synthetic intermediates and the drive to adopt greener methods of synthesis have stimulated a growing interest in biocatalysis as a selective and environmentally benign synthetic technique.

Practical Biotransformations: A Beginner's Guide provides an introduction to microbes and enzymes and demonstrates their practical applications in synthetic organic chemistry. Designed as a laboratory manual, this user-friendly guide discusses standard laboratory techniques, with appropriate advice on aspects of microbial practice and associated safety.

Topics covered include:

• An introduction to equipment in a biotransformations laboratory
• An overview of biocatalyst sources
• Maintenance and growth of biocatalysts
• Example biotransformations using commercially available microbes and enzymes
• Basic gene cloning and the use of ‘designer’ biocatalysts

This book will be a valuable resource for synthetic organic chemists with little or no experience of biochemistry or microbiology. It is the author’s hope that this text will inspire readers to consider biocatalytic methods as real alternatives to traditional synthetic solutions.

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Über die Autorin bzw. den Autor

Gideon Grogan is a lecturer at the University of York, Department of Chemistry. He is also Science Manager of the Bioscience for Business Knowledge Transfer Network (a UK DTI-funded organisation for biocatalysis collaborations between academe and industry) and Deputy Director of the Centre of Excellence for Biocatalysis, Biotransformation and Biomanufacture (at York).

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Biotransformations are reactions catalysed by either enzymes or microbes which are of potential use to preparative synthetic chemistry. Biotransformation science can include microbiological and biochemical techniques with which the organic chemist is unfamiliar, yet this should not be a barrier to the uptake of these processes, the use of which can result in significant research and economic benefits.

The book is aimed at organic chemistry postgraduates and researchers in both academia and industry who are aware of the existence of biotransformation methodology, and of its potential value, but do not know how to begin to implement the relevant experimental techniques in the laboratory. It is written in an accessible and user-friendly way that should facilitate the introduction of biocatalysis in to some new labs.

The book is aimed at organic chemistry postgraduates and researchers in both academia and industry who are aware of the existence of biotransformation methodology, and of its potential value, but do not know how to begin to implement the relevant experimental techniques in the laboratory. It is written in an accessible and user-friendly way that should facilitate the introduction of biocatalysis in to some new labs.

Details zur Ausgabe

• Verlag: Wiley-Blackwell
• Erscheinungsdatum: 2009
• Sprache: Englisch
• ISBN 10: 1405171251
• ISBN 13: 9781405171250
• Einband: Taschenbuch
• Auflage: 1
• Anzahl der Seiten: 344
• Kontakt zum Hersteller: Wiley-VCH GmbH; product_safety@wiley.com; ; Boschstrasse 12; Weinheim; 69469; Deutschland