BetaSys: Systems Biology of Regulated Exocytosis in Pancreatic ß-Cells: 02 - Hardcover

Hardcover

ISBN 10: 1441969551 ISBN 13: 9781441969552

Verlag: Springer, 2011

Inhaltsangabe

BetaSys uses the example of regulated exocytosis in pancreatic β-cells, and its relevance to diabetes, to illustrate the major concepts of systems biology, its methods and applications.

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The insulin secreting ß-cell is one of the most specialized cell types with diverse and multi-functional components (genes, gene products, organelles and metabolites) and a multitude of regulatory strategies in response to internal and environmental signals. This book looks at the technological advances that make simultaneous detection of thousands of biological variables possible; at a substantial variety of mathematical models and numerical simulations that aim to explain major aspects of the ß-cell function; and at the challenge to formulate a comprehensive and robust model of the main networks of the underlying biochemical and physical processes for diagnostic and therapeutic use.

Details zur Ausgabe

• Verlag: Springer
• Erscheinungsdatum: 2011
• Sprache: Englisch
• ISBN 10: 1441969551
• ISBN 13: 9781441969552
• Einband: Tapa dura
• Anzahl der Seiten: 578
• Herausgeber: Booß-Bavnbek Bernhelm, Klösgen Beate, Larsen Jesper
• Kontakt zum Hersteller: Nicht verfügbar
• Verantwortliche Person: CMN Printpool Inh. Mathis Neumann; https://www.also.com/ec/cms5/en_6000/6000/index.jsp; ; Friedrich-Karl-Str. 9; Hamburg; Deutschland