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Human Cell Transformation: Role of Stem Cells and the Microenvironment (Advances in Experimental Medicine and Biology, 720, Band 720) - Hardcover

 
9781461402534: Human Cell Transformation: Role of Stem Cells and the Microenvironment (Advances in Experimental Medicine and Biology, 720, Band 720)
Hardcover
ISBN 10: 1461402530 ISBN 13: 9781461402534
Verlag: Springer, 2011

Inhaltsangabe

Rhim and Kremer’s state-of-the-art volume on Human Cell Transformation: Role of Stem Cells and the Microenvironment highlights the latest findings on the current state of human cell transformation model systems and provides the insight into the molecular and cellular changes involved in the conversion of normal cells to neoplastic cells.

Chapters cover all recently developed novel human cell models. In addition, the rapidly growing fields of knowledge regarding not only stem cells in cancer progression, but also the role of the microenvironments in human carcinogenesis are discussed. A wealth of topics is presented including:

·         Derivation of epithelial, fibroblastic, and hematopoietic in vitro model systems

·         Oncogenes

·         Tumor suppressor genes

·         Viral transformation

·         In vitro model systems for viral, chemical and radiation carcinogenesis

·         Cell aging

·         The multistep nature of human carcinogenesis

·         The role of stem cells and the microenvironment in tumorigenesis

·         The genes involved in multistep carcinogenesis

Unique in both scope and focus – devoted solely to human cell transformation systems – Human Cell Transformation: Role of Stem Cells and the Microenvironment provides unparalleled, in-depth coverage for cancer researchers, cell and molecular biologists, hematologists, virologists, and workers in related fields.

Essential reading for everyone who needs to be kept up-to-date in this fast-paced area!

 

Features


Ø  Multistep models

Ø  Breast cancer/Stem cells

Ø  Prostate cancer/Stem cells

Ø  Multistep / Genes

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Verlag
Springer
Erscheinungsdatum
2011
Sprache
Englisch
ISBN 10 
1461402530
ISBN 13 
9781461402534
Einband
Gebundene Ausgabe
Anzahl der Seiten
246
Herausgeber
Rhim Johng S., Kremer Richard
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