1 Synaptic Interactions between Cortical Neurons.- 1. Introduction.- 1.1. Measures of Synaptic Interactions.- 1.2. Effects of Synaptic Connections.- 2. Visual Cortex.- 2.1. Application of the Cross-Correlation Technique in the Visual System.- 2.2. Geniculocortical Interaction.- 2.3. Corticogeniculate Interaction.- 2.4. Intra- and Intercolumnar Interaction in Single and Adjacent Functional Columns of the Visual Cortex.- 2.5. Transcolumnar Interaction between Distant Columns.- 2.6. Synaptic Interaction Demonstrated by STA.- 2.7. Functional Conclusions.- 3. Auditory Cortex.- 4. Somatosensory Cortex.- 4.1. Cross-Correlation Studies.- 4.2. STA Studies.- 5. Motor Cortex.- 5.1. Cross-Correlation Studies.- 5.2. STA Studies.- 6. Association Cortex.- 7. Hippocampus.- 7.1. Cross-Correlation Studies.- 7.2. STA Studies.- 8. Summary and Conclusions.- 8.1. Common Features of Synaptic Interactions.- 8.2. Future Directions.- 9. References.- 2 The Role of Layer I in Cortical Function.- 1. Introduction.- 2. Behavioral Role of Layer I.- 3. Layer I in Sensory Cortices.- 3.1. Electrophysiology of Layer II Neurons.- 3.2. Afferent Connections and Physiology.- 4. Architecture of Layer I.- 4.1. Subdivisions.- 4.2. Neuronal Composition.- 4.3. Compartmentation of Apical Dendrites.- 5. The Proximal and Distal GABAergic Systems.- 6. Compartmentation of Afferent Connections.- 6.1. Thalamic and Subicular Projections.- 6.2. Serotoninergic Projections to Layer I.- 7. Passive and Active Interactions between Distal and Proximal Dendritic Compartments.- 8. Cholinergic Projections: Organization and Role in Event Holding.- 9. Noradrenergic Projections to Layer I and Memory Consolidation.- 10. What Is the Role of Layer I in Cortical Function?.- 11. References.- 3 Synapse Replacement on Cortical Neurons following Denervation.- 1. Introduction.- 2. The Process of Reinnervation in the Dentate Gyrus of Adult Rats: Nature of the Growth Response of Pre- and Postsynaptic Elements.- 2.1. Documentation of Synapse Replacement on Denervated Neurons Using Quantitative Electron Microscopic Techniques.- 2.2. The Nature of the Growth Response of Pre-and Postsynaptic Elements.- 2.3. Light Microscopic Studies of Afferent Reorganization.- 2.4. Quantitative Electron Microscopic Studies of Terminal Proliferation.- 2.5. Multiple Synapse Formation.- 2.6. Temporal Relationship between Terminal Proliferation and Synapse Replacement.- 2.7. Time Course of Growth of the Participating Systems.- 2.8. Is the Time Course and Extent of Synapse Replacement Constant in Different Settings?.- 2.9. Specificity in the Pattern of Synapse Formation by Reinnervating Fibers.- 2.10. Synapse Formation: Renovation of the Old Synaptic Sites or New Construction.- 2.11. Remodeling the Postsynaptic Cells' Receptive Surface during Reinnervation.- 2.12. Lesion-Induced Growth: Coordinate Growth of Pre- and Postsynaptic Cells.- 3. Role of Glial Cells in Synapse Remodeling.- 3.1. Astrocytes.- 3.2. Microglia.- 4. Cellular and Molecular Mechanisms of Lesion-Induced Growth.- 5. Cellular and Molecular Processes Associated with the Phase of Terminal Degeneration, Dendritic Atrophy, and Glial Proliferation and Hypertrophy.- 5.1. Potential Initiating Signals.- 5.2. Molecular Processes That Lead to Dendritic Atrophy.- 5.3. Molecular Events within Reactive Glial Cells.- 5.4. Changes in Astrocyte Mitogenic and Morphogenetic Factors following Injury.- 6. Cellular and Molecular Processes Associated with the Phase of Terminal Proliferation, Synaptogenesis, and Dendritic Regrowth.- 6.1. Events within Sprouting Neurons.- 6.2. Events within the Postsynaptic Neurons and the Denervated Neuropil.- 6.3. Possible Role of Neuronotrophic Substances and Growth Factors.- 7. Conclusion.- 8. References.- 4 Olfactory Frontal Cortex and Multiple Olfactory Processing in Primates.- 1. Introduction.- 2. Olfactory Frontal Cortex in Primates.- 2.1. Search for an Olfactory Projection Area in the Neocortex.- 2.2. A Study on the Olfactory Pathway to the
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